ArticleThe British journal of radiology2014
Multimodality imaging features, metastatic pattern and clinical outcome in adult extraskeletal Ewing sarcoma: experience in 26 patients.
Article in The British journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- MRI findings for differentiating benign and malignant soft tissue tumors: a systematic review-part 2: key imaging findings.Skeletal radiology · 2026Pooled it
- Soft tissue reporting and data system (soft tissue-RADS): framework for radiologists specializing in imaging of musculoskeletal tumors and tumor-like lesions.Skeletal radiology · 2026Review
- Extraosseous Ewing's Sarcoma of the Chest Wall: A Case Report and Review of Literature.Cureus · 2025Article
- Article
- Radiological findings in children with primary mediastinal Ewing sarcoma/primitive neuroectodermal tumors: a retrospective case series study.Quantitative imaging in medicine and surgery · 2025Article
- Undifferentiated small round cell sarcomas in the retroperitoneal space in a 12-year-old female: a rare case report.Frontiers in pediatrics · 2025Article
- Article
- Primary adrenal Ewing sarcoma: A systematic review of the literature.World journal of clinical cases · 2023Article
- Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) of the bladder in an adolescent: a case description.Quantitative imaging in medicine and surgery · 2023Article
- Extraskeletal Ewing sarcoma presenting as an axillary mass with pulmonary metastases.BMJ case reports · 2023Article
- Extraskeletal Ewing sarcoma of the sciatic nerve.Radiology case reports · 2023Article
- Case report: Primary pleural giant extraskeletal Ewing sarcoma in a child.Frontiers in oncology · 2023Article
- Extra-skeletal Ewing's sarcoma of the leg with multiple skeletal and pulmonary metastases: A rare pediatric case report.SAGE open medical case reports · 2023Article
- A Rare Presentation of Extraosseous Ewing Sarcoma Manifesting as a Dumbbell Tumor on the Nape of the Neck.Case reports in surgery · 2022Article
- Ewing's Sarcoma of the Breast in a Young Woman: A Case Report and Review of the Literature.Frontiers in oncology · 2022Article
- Extraskeletal Ewing's sarcoma: outcomes and CT features of endoceliac lesions.Translational cancer research · 2021Article
- Mediastinal lymph node metastasis as a single expression of disease relapse in Ewing's sarcoma: multidisciplinary approach of two consecutive cases.Intractable & rare diseases research · 2021Article
- Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis.Oncology letters · 2021Review
- Imaging features and clinical course of undifferentiated round cell sarcomas with CIC-DUX4 and BCOR-CCNB3 translocations.Skeletal radiology · 2021Article
- Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the multimodality imaging features, metastatic pattern and clinical outcome in adult extraskeletal Ewing sarcoma (EES).
methodsIn this institutional review board-approved, health insurance portability and accountability act-compliant retrospective study, we included 26 patients (17 females and 9 males; mean age, 36 years; range, 18-85 years) with pathologically confirmed EES seen at our institute between 1999 and 2011, who had imaging of primary tumour. Imaging of primary tumour in all 26 patients and follow-up imaging in 23 was reviewed by two radiologists in consensus. Clinical data were extracted from electronic medical records.
resultsThe most common primary sites were the torso (n = 13), extremities (n = 10) and head and neck (HN) region (n = 3). The mean tumour size was 9 cm (range, 3-22 cm); tumours of the torso were larger than those of other areas (p > 0.05). Compared with the skeletal muscle, tumours were isodense on CT (21/21), hypointense (n = 5) to isointense (n = 14) on T1 weighted image, hyperintense on T2 weighted image (19/19) and were fluorine-18 fludeoxyglucose ((18)F-FDG)-avid [10/10; mean maximum standardized uptake value of 7 (range, 3-11)]. Necrosis (15/26), haemorrhage (5/26) and adjacent organ invasion (14/26) were present without calcification. Median follow-up was 16 months. 5 patients had local recurrence (torso, 3; extremity, 1; and HN, 1). Metastases developed in 11 patients (torso, 7; extremities, 3; and HN, 1; p > 0.05); 8 at presentation, most commonly to lung (9/11), peritoneum (4/11), muscles (4/11) and lymph nodes (4/11). Nine patients (torso, 7; extremity, 1; and HN, 1) died (10 months median survival) (p > 0.05).
conclusionAdult EESs are large tumours, which frequently invade adjacent organs and metastasize to the lung. EESs of the torso are larger, have more frequent metastases and poorer outcomes. ADVANCES IN KNOWLEDGE: Adult EESs of the torso have poor outcomes compared with other EESs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.