Evidence map›Paper›PMID 24734886›Full record

ReviewExpert review of clinical immunology2014

Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis.

Damian Maseda, Rachel H Bonami, Leslie J Crofford

Abstract readReview
In one paragraph

Review in Expert review of clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. [Clinical characteristics and risk factors of rheumatoid arthritis with ulcerative keratitis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Recurrent and refractory corneal perforation secondary to rheumatoid arthritis treated with infliximab.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Damian MasedaDepartment of Medicine, Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Rachel H Bonami
Leslie J Crofford
Vanderbilt University Medical Center · US

Funding

Prostaglandin E synthase in rheumatoid arthritisR01AR049010 · NIAMS · VANDERBILT UNIVERSITY · PI CROFFORD, LESLIE J · 2004 to 2014
$2.9M
NIAMS NIH HHS AR049010NIAMS NIH HHS R01 AR049010
6 · The paper itself

Abstract

B cells mediate multiple functions that influence immune and inflammatory responses in rheumatoid arthritis. Production of a diverse array of autoantibodies can happen at different stages of the disease, and are important markers of disease outcome. In turn, the magnitude and quality of acquired humoral immune responses is strongly dependent on signals delivered by innate immune cells. Additionally, the milieu of cells and chemokines that constitute a niche for plasma cells rely strongly on signals provided by stromal cells at different anatomical locations and times. The chronic inflammatory state therefore importantly impacts the developing humoral immune response and its intensity and specificity. We focus this review on B cell biology and the role of the innate immune system in the development of autoimmunity in patients with rheumatoid arthritis.

Indexed as

Immunity, InnateAnimalsArthritis, RheumatoidAutoantibodiesB-Lymphocyte SubsetsChemokinesChronic DiseaseHumansPlasma CellsSignal TransductionStromal CellsAutoantibodiesChemokinesautoantibodiesB cellsinflammationinnate immunityplasma cells

Identifiers

PMID24734886
PMCPMC5073792
OpenAlexW2171758194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.