ArticlePigment cell & melanoma research2014
Tetraspanin 3c requirement for pigment cell interactions and boundary formation in zebrafish adult pigment stripes.
Article in Pigment cell & melanoma research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Correlation between DNA methylation and transcriptomic changes in golden Asian sea bass (Lates calcarifer): An integrated approach.Journal of fish biology · 2026Article
- Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake.Genome biology · 2025Article
- Tetraspanin Cd9b plays a role in fertility in zebrafish.PloS one · 2022Article
- A complex genetic architecture in zebrafish relatives Danio quagga and D. kyathit underlies development of stripes and spots.PLoS genetics · 2021Article
- Article
- Neural innervation as a potential trigger of morphological color change and sexual dimorphism in cichlid fish.Scientific reports · 2020Article
- Article
- What lies beneath? Molecular evolution during the radiation of caecilian amphibians.BMC genomics · 2019Article
- Iridophores as a source of robustness in zebrafish stripes and variability in Danio patterns.Nature communications · 2018Article
- Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish.Biology open · 2016Article
- The Physiological Characterization of Connexin41.8 and Connexin39.4, Which Are Involved in the Striped Pattern Formation of Zebrafish.The Journal of biological chemistry · 2016Article
- Modelling stripe formation in zebrafish: an agent-based approach.Journal of the Royal Society, Interface · 2015Article
- Origins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolution.Pigment cell & melanoma research · 2015Review
- Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish.eLife · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Skin pigment pattern formation in zebrafish requires pigment-cell autonomous interactions between melanophores and xanthophores, yet the molecular bases for these interactions remain largely unknown. Here, we examined the dali mutant that exhibits stripes in which melanophores are intermingled abnormally with xanthophores. By in vitro cell culture, we found that melanophores of dali mutants have a defect in motility and that interactions between melanophores and xanthophores are defective as well. Positional cloning and rescue identified dali as tetraspanin 3c (tspan3c), encoding a transmembrane scaffolding protein expressed by melanophores and xanthophores. We further showed that dali mutant Tspan3c expressed in HeLa cell exhibits a defect in N-glycosylation and is retained inappropriately in the endoplasmic reticulum. Our results are the first to identify roles for a tetraspanin superfamily protein in skin pigment pattern formation and suggest new mechanisms for the establishment and maintenance of zebrafish stripe boundaries.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.