ReviewJournal of ophthalmology2014
Gender differences in vogt-koyanagi-harada disease and sympathetic ophthalmia.
Review in Journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Clinical and OCT Predictors of Refractory Vogt-Koyanagi-Harada Disease.Ophthalmology science · 2026Article
- Managing Vogt-Koyanagi-Harada disease during pregnancy with steroid pulse therapy: A case report.World journal of clinical cases · 2024Article
- An Overview of the Biological Complexity of Vitiligo.Oxidative medicine and cellular longevity · 2024Review
- Autoimmune Disease Classification Based on PubMed Text Mining.Journal of clinical medicine · 2022Article
- Use of systemic corticosteroids in patients newly registered at a claims database with a diagnosis of non-infectious uveitis: results from a real-world claims database analysis.Japanese journal of ophthalmology · 2022Observational
- Sympathetic ophthalmia: A comprehensive update.Indian journal of ophthalmology · 2022Review
- Identification of immune hub genes participating in the pathogenesis and progression of Vogt-Koyanagi-Harada disease.Frontiers in immunology · 2022Article
- Incomplete Vogt-Koyanagi-Harada in a 14-year-Old African American female with bilateral disc edema.American journal of ophthalmology case reports · 2021Article
- Sympathetic Ophthalmia: Where Do We Currently Stand on Treatment Strategies?Clinical ophthalmology (Auckland, N.Z.) · 2021Review
- Treatment of Vogt-Koyanagi-Harada Disease.Cureus · 2020Article
- Bilateral Sterile Pyogranulomatous Keratitis in a Dog.Case reports in veterinary medicine · 2019Article
- Sympathetic ophthalmia in fellow eye after vitrectomy for massive subretinal hemorrhage secondary to polypoidal choroidal vasculopathy.International medical case reports journal · 2018Article
- Vogt-Koyanagi-Harada syndrome - current perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2016Review
- The role of sex in uveitis and ocular inflammation.International ophthalmology clinics · 2015Review
- Influence of molecular genetics in Vogt-Koyanagi-Harada disease.Journal of ophthalmic inflammation and infection · 2014Review
- Clinical and multimodal imaging characteristics of eyes with Vogt-Koyanagi-Harada disease: An Egyptian experience.Oman journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Vogt-Koyanagi-Harada disease (VKH) and sympathetic ophthalmia (SO) are types of T-cell mediated autoimmune granulomatous uveitis. Although the two diseases share common clinical features, they have certain differences in gender predilections. VKH classically has been reported as more prevalent in females than males, yet some studies in Japan and China have not found differences in gender prevalence. Male patients have a higher risk of chorioretinal degeneration, vitiligo, and worse prognosis. Conversely, the changing levels of estrogen/progesterone during pregnancy and the menstrual cycle as well as higher levels of TGF-β show a protective role in females. Potential causes of female predilection for VKH are associated with HLA-DR and HLA-DQ alleles. SO, a bilateral granulomatous uveitis, occurs in the context of one eye after a penetrating injury due to trauma or surgery. In contrast to the female dominance in VKH, males are more frequently affected by SO due to a higher incidence of ocular injury, especially during wartime. However, no gender predilection of SO has been reported in postsurgical cases. No clinically different manifestations are revealed between males and females in SO secondary to either ocular trauma or surgery. The potential causes of the gender difference may provide hints on future treatment and disease evaluation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.