ArticleApplied clinical informatics2014
Home blood pressure monitoring, secure electronic messaging and medication intensification for improving hypertension control: a mediation analysis.
Article in Applied clinical informatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Evaluating the Impact of the COVID-19 Pandemic on Telepharmaceutical Service Effectiveness: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Interactive Remote Patient Monitoring Devices for Managing Chronic Health Conditions: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- Consumer Devices for Patient-Generated Health Data Using Blood Pressure Monitors for Managing Hypertension: Systematic Review.JMIR mHealth and uHealth · 2022Pooled it
- Adult patient access to electronic health records.The Cochrane database of systematic reviews · 2021Pooled it
- How Behavior Change Strategies are Used to Design Digital Interventions to Improve Medication Adherence and Blood Pressure Among Patients With Hypertension: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Impact of Patient-Clinical Team Secure Messaging on Communication Patterns and Patient Experience: Randomized Encouragement Design Trial.Journal of medical Internet research · 2020Trial
- A Successful Multifaceted Trial to Improve Hypertension Control in Primary Care: Why Did it Work?Journal of general internal medicine · 2015Trial
- A scoping review of studies on secure messaging through patient portals: persistent challenges and potential solutions.npj health systems · 2026Article
- Remote Patient Monitoring Program Components and Short-Term Hypertension Control: Retrospective Cohort Study.JMIR mHealth and uHealth · 2026Article
- Association of Mobile-Enhanced Remote Patient Monitoring with Blood Pressure Control in Hypertensive Patients with Comorbidities: A Multicenter Pre-Post Evaluation.Diagnostics (Basel, Switzerland) · 2026Article
- Clinical Decision Support Systems Using Home Blood Pressure Readings to Manage Patients With Hypertension: Scoping Review.Journal of medical Internet research · 2025Article
- Self-Monitoring Practices and Use of Self-Monitoring Technologies by People with Rheumatic and Musculoskeletal Diseases: An International Survey Study.Healthcare (Basel, Switzerland) · 2024Article
- Conquering hypertension in Vietnam: 12- month follow up results from a cluster-randomised controlled trial.The Lancet regional health. Western Pacific · 2024Article
- Telehealth Use to Address Cardiovascular Disease and Hypertension in the United States: A Systematic Review and Meta-Analysis, 2011-2021.Telemedicine reports · 2023Review
- The Perceived Effectiveness of Secure Messaging for Medication Reconciliation During Transitions of Care: Semistructured Interviews With Patients.JMIR human factors · 2022Article
- Pharmacist involvement in a comprehensive remote monitoring and telemanagement program.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2022Article
- Patient and Clinician Characteristics Associated With Secure Message Content: Retrospective Cohort Study.Journal of medical Internet research · 2021Article
- Assessing Data Adequacy for High Blood Pressure Clinical Decision Support: A Quantitative Analysis.Applied clinical informatics · 2021Article
- The current state and future of internet technology-based hypertension management in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe evaluated the role of home monitoring, communication with pharmacists, medication intensification, medication adherence and lifestyle factors in contributing to the effectiveness of an intervention to improve blood pressure control in patients with uncontrolled essential hypertension.
methodsWe performed a mediation analysis of a published randomized trial based on the Chronic Care Model delivered over a secure patient website from June 2005 to December 2007. Study arms analyzed included usual care with a home blood pressure monitor and usual care with home blood pressure monitor and web-based pharmacist care. Mediator measures included secure messaging and telephone encounters; home blood pressure monitoring; medications intensification and adherence and lifestyle factors. Overall fidelity to the Chronic Care Model was assessed with the Patient Assessment of Chronic Care (PACIC) instrument. The primary outcome was percent of participants with blood pressure (BP) <140/90 mm Hg.
resultsAt 12 months follow-up, patients in the web-based pharmacist care group were more likely to have BP <140/90 mm Hg (55%) compared to patients in the group with home blood pressure monitors only (37%) (p = 0.001). Home blood pressure monitoring accounted for 30.3% of the intervention effect, secure electronic messaging accounted for 96%, and medication intensification for 29.3%. Medication adherence and self-report of fruit and vegetable intake and weight change were not different between the two study groups. The PACIC score accounted for 22.0 % of the main intervention effect.
conclusionsThe effect of web-based pharmacist care on improved blood pressure control was explained in part through a combination of home blood pressure monitoring, secure messaging, and antihypertensive medication intensification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.