ArticleEvidence-based complementary and alternative medicine : eCAM2014
Acupuncture modulates the functional connectivity of the default mode network in stroke patients.
Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Neural effects of acupuncture on stroke patients with motor dysfunction: an activation likelihood estimation meta-analysis.Frontiers in neurology · 2024Pooled it
- Analysis of correlation between structural changes and functional response in post-stroke motor recovery after cM1 LF-rTMS: an exploratory randomized trial.Scientific reports · 2026Trial
- Altered Effective Connectivity Within the Frontoparietal Network in Alzheimer's Disease and Its Modulation by Acupuncture: A Resting-StateNeuropsychiatric disease and treatment · 2026Trial
- Effect of robot-assisted gait training combined with electroacupuncture on lower limb motor function and brain network characteristics in stroke: an EEG study.Journal of neuroengineering and rehabilitation · 2025Trial
- Electroacupuncture Modulates Multiple Pathways for Neuroprotection and Neurorepair in Ischemic Stroke.CNS neuroscience & therapeutics · 2026Review
- Structural-Functional Dissociation in TBI Hemiplegia: Meridian-Sinew Therapy Promotes Motor Recovery Despite Corticospinal Tract Damage-A Case Report.Clinical case reports · 2025Article
- Resting-State fMRI Reveals the Neural Correlates of Acupuncture in the Treatment of Vascular Cognitive Impairment.Clinical interventions in aging · 2025Review
- A resting-state fMRI cross-sectional study of cardiorespiratory fitness decline after stroke.Frontiers in neurology · 2025Article
- Magnetic resonance imaging studies on acupuncture therapy in cerebral ischemic stroke: A systematic review.Heliyon · 2024Article
- Altered Functional Activity and Functional Connectivity of Seed Regions Based on ALFF Following Acupuncture Treatment in Patients with Stroke Sequelae with Unilateral Limb Numbness.Neuropsychiatric disease and treatment · 2023Article
- Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study.Frontiers in neurology · 2022Article
- The altered intrinsic functional connectivity after acupuncture at shenmen (HT7) in acute sleep deprivation.Frontiers in neurology · 2022Article
- A scoping review of the contralateral effects of unilateral peripheral stimulation on neuromuscular function.PloS one · 2022Article
- Article
- Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI.Neural plasticity · 2021Review
- Resting-State fMRI in Studies of Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Acupuncture WithFrontiers in neuroscience · 2021Article
- Progress of Acupuncture Therapy in Diseases Based on Magnetic Resonance Image Studies: A Literature Review.Frontiers in human neuroscience · 2021Review
- Magnetic Resonance Imaging Studies on Acupuncture Therapy in Depression: A Systematic Review.Frontiers in psychiatry · 2021Review
- Scalp Acupuncture Enhances the Functional Connectivity of Visual and Cognitive-Motor Function Network of Patients with Acute Ischemic Stroke.Evidence-based complementary and alternative medicine : eCAM · 2020Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abundant evidence from previous fMRI studies on acupuncture has revealed significant modulatory effects at widespread brain regions. However, few reports on the modulation to the default mode network (DMN) of stroke patients have been investigated in the field of acupuncture. To study the modulatory effects of acupuncture on the DMN of stroke patients, eight right hemispheric infarction and stable ischemic stroke patients and ten healthy subjects were recruited to undergo resting state fMRI scanning before and after acupuncture stimulation. Functional connectivity analysis was applied with the bilateral posterior cingulate cortices chosen as the seed regions. The main finding demonstrated that the interregional interactions between the ACC and PCC especially enhanced after acupuncture at GB34 in stroke patients, compared with healthy controls. The results indicated that the possible mechanisms of the modulatory effects of acupuncture on the DMN of stroke patients could be interpreted in terms of cognitive ability and motor function recovery.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.