ArticleIranian journal of pharmaceutical research : IJPR2014
Plasma Vitamin D Status and Its Correlation with Risk Factors of Thrombosis, P-selectin and hs-CRP Level in Patients with Venous Thromboembolism; the First Study of Iranian Population.
Article in Iranian journal of pharmaceutical research : IJPR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Is Circulating Vitamin D Status Associated with the Risk of Venous Thromboembolism? A Meta-Analysis of Observational Studies.Nutrients · 2023Pooled it
- Recent Updates and Advances in the Association Between Vitamin D Deficiency and Risk of Thrombotic Disease.Nutrients · 2024Review
- Review
- Low levels of vitamin D were associated with coagulopathy among hospitalized coronavirus disease-19 (COVID-19) patients: A single-centered study in Indonesia.Journal of medical biochemistry · 2021Article
- Is There a Crucial Link Between Vitamin D Status and Inflammatory Response in Patients With COVID-19?Frontiers in immunology · 2021Observational
- Article
- MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19.European journal of endocrinology · 2020Review
- High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis.Iranian journal of medical sciences · 2018Review
- Vitamin D Deficiency Predicts the ST Elevation Type of Myocardial Infarction in Patients with Acute Coronary Syndrome.Iranian journal of pharmaceutical research : IJPR · 2018Article
- Role of microRNA-26a in the diagnosis of lower extremity deep vein thrombosis in patients with bone trauma.Experimental and therapeutic medicine · 2017Article
- The Role of Toll-Like Receptors and Vitamin D in Cardiovascular Diseases-A Review.International journal of molecular sciences · 2017Review
- Benefits from the correction of vitamin D deficiency in patients with pulmonary hypertension.Caspian journal of internal medicine · 2016Article
- The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature.Disease markers · 2015Review
- Association between vitamin D levels and lower-extremity deep vein thrombosis: a case-control study.Sao Paulo medical journal = Revista paulista de medicinaArticle
- Correlations of CT scan with high-sensitivity C-reactive protein and D-dimer in patients with coronavirus disease 2019.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low plasma level of vitamin D is linked to the increased risk of cardiovascular diseases such as hypertension, diabetes, dyslipidemia and peripheral vascular diseases. Vitamin D deficiency is a worldwide problem that involves Iranian population. To the best of our knowledge, this was the first investigation on venous thromboembolism (VTE) subjects that assessed the correlation of vitamin D level with plasma P-selectin, hs-CRP, and risk factors of thrombosis. In this prospective pilot study, patients with diagnosis of acute deep vein thrombosis and/ or pulmonary embolism were enrolled. All patients' clinical data, demographics and risk factors of thrombosis were evaluated. Plasma level of P-selectin and hs-CRP were measured by ELISA method. Radio immune assay method was used to determine plasma level of 25-hydroxy vitamin D (25(OH) D). In this study, 60 subjects were included. The mean ± SD plasma 25-hydroxy vitamin D level (25(OH) D) of participants was 21.4 ± 14.6 ng/mL. The vitamin D deficiency was detected in 60% of patients. No significant relation was found between the plasma 25(OH)D level and P-selectin and hs-CRP. In multiple regression analysis, there was a significant relationship between the level of 25(OH)D and the patients' age (beta = 0.452; p = 0.001), diabetes (beta = 0.280; p = 0.036) and positive family history of cardiovascular diseases (beta = 0.373; p = 0.003). Vitamin D deficiency is a frequent problem in Iranian VTE patients. Moreover, Plasma level of vitamin D is not associated with P-selectin and hs-CRP in VTE patients.
Indexed as
Identifiers
24734087PMC3985233W2109923594What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.