ArticleIranian journal of pharmaceutical research : IJPR2014
Validated spectrophtometric method for determination of tamsulosin in bulk and pharmaceutical dosage forms.
Article in Iranian journal of pharmaceutical research : IJPR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Green HPLC-Fluorescence detection method for concurrent analysis of Tamsulosin hydrochloride and Tolterodine tartrate in dosage forms and biological fluids.Scientific reports · 2025Article
- Development of Green HPTLC method for simultaneous determination of a promising combination Tamsulosin and Mirabegron: stability-indicating assay was examined.BMC chemistry · 2023Article
- Validated Spectrophtometric Method for Simultaneous Determination of Buprenorphine and Naloxone in Pharmaceutical Dosage Forms.Iranian journal of pharmaceutical research : IJPR · 2017Article
- Development of a rapid derivative spectrophotometric method for simultaneous determination of acetaminophen, diphenhydramine and pseudoephedrine in tablets.Iranian journal of pharmaceutical research : IJPR · 2015Article
- UV Spectrophotometric Determination and Validation of Hydroquinone in Liposome.Iranian journal of pharmaceutical research : IJPR · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
In this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at pH 3.5. The formed yellow color complex was extracted with chloroform and measured at 415 nm. The optimum reaction conditions such as pH, reagent amount, extracting solvent and the stoichiometry of the ion-pair complex were investigated. Under the optimized conditions, the Beer's law was obeyed in the concentration range of 1-160 g/mL with acceptable correlation coefficient (r(2) > 0.9997) and precision (CV < 3%) and accuracy (error < 2%). The proposed method was successfully used for the determination of tamsulosin in pharmaceutical capsule with nosignificant interferences of excipients.
Indexed as
Identifiers
24734058PMC3985241What OpenQuestion holds
Registered trials
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