ArticleFrontiers in psychology2014
Differences in cerebral cortical anatomy of left- and right-handers.
Article in Frontiers in psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
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Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Significant heterogeneity in structural asymmetry of the habenula in the human brain: A systematic review and meta-analysis.Human brain mapping · 2023Pooled it
- Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.Proceedings of the National Academy of Sciences of the United States of America · 2018Pooled it
- Higher VOScientific reports · 2021Trial
- Reduced brain microstructural asymmetry in patients with childhood leukemia treated with chemotherapy compared with healthy controls.PloS one · 2019Trial
- Lifespan Trajectories of Asymmetry in White Matter Tracts.Human brain mapping · 2026Article
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- Side dominance and eye patches obscuring half of the visual field do not affect walking kinematics.Scientific reports · 2025Article
- Comparison of structural brain volume among sedentary normal, overweight and obese adults - A cross-sectional study.Journal of education and health promotion · 2025Article
- Neuroanatomical correlates of musicianship in left-handers.Behavioral and brain functions : BBF · 2024Article
- Hand preference and the corpus callosum: Is there really no association?Neuroimage. Reports · 2023Article
- Accelerated atrophy in dopaminergic targets and medial temporo-parietal regions precedes the onset of delusions in patients with Alzheimer's disease.European archives of psychiatry and clinical neuroscience · 2023Article
- Workload-dependent hemispheric asymmetries during the emotion-cognition interaction: a close-to-naturalistic fNIRS study.Frontiers in neuroergonomics · 2023Article
- Article
- Relations between hemispheric asymmetries of grey matter and auditory processing of spoken syllables in 281 healthy adults.Brain structure & function · 2022Article
- Dose-dependent relationship between social drinking and brain aging.Neurobiology of aging · 2022Article
- Is it left or is it right? A classification approach for investigating hemispheric differences in low and high dimensionality.Brain structure & function · 2022Article
- Broca's area and the search for anatomical asymmetry: commentary and perspectives.Brain structure & function · 2022Article
- Polygenic scores for handedness and their association with asymmetries in brain structure.Brain structure & function · 2022Article
- Classifying handedness with MRI.Neuroimage. Reports · 2021Article
- Handedness and its genetic influences are associated with structural asymmetries of the cerebral cortex in 31,864 individuals.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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11 authors.
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Abstract
The left and right sides of the human brain are specialized for different kinds of information processing, and much of our cognition is lateralized to an extent toward one side or the other. Handedness is a reflection of nervous system lateralization. Roughly ten percent of people are mixed- or left-handed, and they show an elevated rate of reductions or reversals of some cerebral functional asymmetries compared to right-handers. Brain anatomical correlates of left-handedness have also been suggested. However, the relationships of left-handedness to brain structure and function remain far from clear. We carried out a comprehensive analysis of cortical surface area differences between 106 left-handed subjects and 1960 right-handed subjects, measured using an automated method of regional parcellation (FreeSurfer, Destrieux atlas). This is the largest study sample that has so far been used in relation to this issue. No individual cortical region showed an association with left-handedness that survived statistical correction for multiple testing, although there was a nominally significant association with the surface area of a previously implicated region: the left precentral sulcus. Identifying brain structural correlates of handedness may prove useful for genetic studies of cerebral asymmetries, as well as providing new avenues for the study of relations between handedness, cerebral lateralization and cognition.
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