ArticleProceedings of the National Academy of Sciences of the United States of America2014
Control of vacuolar dynamics and regulation of stomatal aperture by tonoplast potassium uptake.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
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Who cites it
94 citing papers in PubMed, 246 citations in OpenAlex.
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- Translational insights into abiotic interactions: From Arabidopsis to crop plants.The Plant cell · 2025Review
- The regulation of vacuole morphology in stigma papilla cells is involved in water transfer to pollen in Arabidopsis thaliana.Plant reproduction · 2025Article
- Structural basis for malate-driven, pore lipid-regulated activation of the Arabidopsis vacuolar anion channel ALMT9.Nature communications · 2025Article
- Optimizing the application of potassium sulfate fertilizer based on the variation in soil mineral accumulation and tobacco growth: a 10-year field experiment.Frontiers in plant science · 2025Article
- The vacuolar KScience advances · 2024Article
- The potassium transporter TaNHX2 interacts with TaGAD1 to promote drought tolerance via modulating stomatal aperture in wheat.Science advances · 2024Article
- Arabidopsis COP1 guides stomatal response in guard cells through pH regulation.Communications biology · 2024Article
- Effects of the combination of biochar and organic fertilizer on soil properties and agronomic attributes of soybean (Glycine max L.).PloS one · 2024Article
- Small holes, big impact: Stomata in plant-pathogen-climate epic trifecta.Molecular plant · 2024Review
- Enhanced Stomatal Conductance Supports Photosynthesis in Wheat to Improved NHPlants (Basel, Switzerland) · 2023Article
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- The Features of Potassium Dynamics in 'Soil-Plant' System of Sour Cherry Orchard.Plants (Basel, Switzerland) · 2023Article
34 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
Abstract
Stomatal movements rely on alterations in guard cell turgor. This requires massive K(+) bidirectional fluxes across the plasma and tonoplast membranes. Surprisingly, given their physiological importance, the transporters mediating the energetically uphill transport of K(+) into the vacuole remain to be identified. Here, we report that, in Arabidopsis guard cells, the tonoplast-localized K(+)/H(+) exchangers NHX1 and NHX2 are pivotal in the vacuolar accumulation of K(+) and that nhx1 nhx2 mutant lines are dysfunctional in stomatal regulation. Hypomorphic and complete-loss-of-function double mutants exhibited significantly impaired stomatal opening and closure responses. Disruption of K(+) accumulation in guard cells correlated with more acidic vacuoles and the disappearance of the highly dynamic remodelling of vacuolar structure associated with stomatal movements. Our results show that guard cell vacuolar accumulation of K(+) is a requirement for stomatal opening and a critical component in the overall K(+) homeostasis essential for stomatal closure, and suggest that vacuolar K(+) fluxes are also of decisive importance in the regulation of vacuolar dynamics and luminal pH that underlie stomatal movements.
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