ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2014
Volume-outcome associations after major hepatectomy for hepatocellular carcinoma: a nationwide Taiwan study.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Volume-outcome relationship in anatomical and non-anatomical liver resections: a rapid systematic review.BMC gastroenterology · 2026Pooled it
- [Centralization of liver surgery in Germany].Chirurgie (Heidelberg, Germany) · 2026Review
- Evaluation of the American College of Surgeons risk calculator in hepatectomy for metastatic colorectal cancer in a Southeast Asian population.Langenbeck's archives of surgery · 2024Article
- Facility Volume Thresholds for Optimization of Short- and Long-Term Outcomes in Patients Undergoing Hepatectomy for Primary Liver Tumors.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Article
- Regional Differences in Admissions and Treatment Outcomes for Hepatocellular Carcinoma Patients in Thailand.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- 5-year recurrence prediction after hepatocellular carcinoma resection: deep learning vs. Cox regression models.American journal of cancer research · 2022Article
- Decentralization and Regionalization of Surgical Care: A Review of Evidence for the Optimal Distribution of Surgical Services in Low- and Middle-Income Countries.International journal of health policy and management · 2019Review
- Impact of pediatric cardiac surgery regionalization on health care utilization and mortality.Health services research · 2019Article
- Clinical outcomes after major hepatectomy are acceptable in low-volume centers in the Caribbean.World journal of hepatology · 2019Article
- Presence of a fellowship improves perioperative outcomes following hepatopancreatobiliary procedures.Surgical endoscopy · 2017Article
- Predictive model for 5-year mortality after breast cancer surgery in Taiwan residents.Chinese journal of cancer · 2017Article
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5 authors.
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Abstract
objectiveThe objective of this study was to explore volume-outcome associations after major hepatectomy for hepatocellular carcinoma (HCC).
methodsThis population-based cohort study retrospectively analyzed 23,107 major hepatectomies for HCC patients from 1998 to 2009. Relationships between hospital/surgeon volume and patient outcome were analyzed by propensity score matching (PSM). Five-year overall survival (OS) was estimated by Kaplan-Meier method, and differences were compared by log-rank test.
resultsThe mean length of stay (LOS) after major hepatectomy was 18.1 days, and the mean hospital cost was US$5,088.2. After PSM, the mean OS in high- and low-volume hospitals was 71.1 months (standard deviation (SD) 0.7 months) and 68.6 months (SD 0.6 months), respectively; the mean OS in high- and low-volume surgeons was 78.5 months (SD 0.7 months) and 66.9 months (SD 0.7 months), respectively. The PSM analysis showed that treatment by high-volume hospitals and treatment by high-volume surgeons were both associated with significantly shorter LOS, lower hospital cost, and longer survival compared to their low-volume counterparts (P < 0.001).
conclusionsThe results of this nationwide study support the regionalization of HCC treatment by hospital volume and by surgeon volume. High surgeon volume revealed both short- and long-term benefits. The applicability of PSM in volume-outcome analysis may also be confirmed.
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