Evidence map›Paper›PMID 24733154›Full record

ArticlePloS one2014

Colonisation of a phage susceptible Campylobacter jejuni population in two phage positive broiler flocks.

Sophie Kittler, Samuel Fischer, Amir Abdulmawjood, Gerhard Glünder, Günter Klein

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Therapeutic and protective approaches to combatFrontiers in pharmacology · 2025
    Review
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  4. Microbiota from Specific Pathogen-Free Mice ReducesPathogens (Basel, Switzerland) · 2021
    Article
  5. Isolation and Characterization of Group IIIFrontiers in microbiology · 2021
    Article
  6. Phage Biocontrol of Campylobacter: A One Health Approach.Current topics in microbiology and immunology · 2021
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sophie KittlerInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, Hannover, Germany.
Samuel FischerClinic for Poultry, University of Veterinary Medicine Hannover, Hannover, Germany.
Amir AbdulmawjoodInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, Hannover, Germany.
Gerhard GlünderClinic for Poultry, University of Veterinary Medicine Hannover, Hannover, Germany.
Günter KleinInstitute of Food Quality and Food Safety, University of Veterinary Medicine Hannover, Hannover, Germany.
University of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogens Campylobacter jejuni and Campylobacter coli are commensals in the poultry intestine and campylobacteriosis is one of the most frequent foodborne diseases in developed and developing countries. Phages were identified to be effective in reducing intestinal Campylobacter load and this was evaluated, in the first field trials which were recently carried out. The aim of this study was to further investigate Campylobacter population dynamics during phage application on a commercial broiler farm. This study determines the superiority in colonisation of a Campylobacter type found in a field trial that was susceptible to phages in in vitro tests. The colonisation factors, i.e. motility and gamma glutamyl transferase activity, were increased in this type. The clustering in phylogenetic comparisons of MALDI-TOF spectra did not match the ST, biochemical phenotype and phage susceptibility. Occurrence of Campylobacter jejuni strains and phage susceptibility types with different colonisation potential seem to play a very important role in the success of phage therapy in commercial broiler houses. Thus, mechanisms of both, phage susceptibility and Campylobacter colonisation should be further investigated and considered when composing phage cocktails.

Indexed as

AlgorithmsAnimalsBacterial Typing TechniquesCampylobacter InfectionsCampylobacter jejuniCluster AnalysisComputational BiologyFood Microbiologygamma-GlutamyltransferasePhenotypePhylogenyPoultryPoultry DiseasesReproducibility of ResultsSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionizationgamma-Glutamyltransferase

Identifiers

PMID24733154
PMCPMC3986380
OpenAlexW2045084928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.