Evidence map›Paper›PMID 24733020›Full record

ArticleAnnals of gastroenterology2014

Population differences concerning TNF-α gene polymorphisms in gastric carcinogenesis based on meta-analysis.

Theodoros Rokkas, Panos Sechopoulos, Dimitrios Pistiolas, Fotis Kothonas, Georgios Margantinis, Georgios Koukoulis

Open access · greenAbstract read
In one paragraph

Article in Annals of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. IL-17A G197A and C1249T polymorphisms in gastric carcinogenesis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Pooled it
  3. The role of TLRs (microbe recognition receptor) in gastric cancer: An update.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Theodoros RokkasGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Panos SechopoulosGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Dimitrios PistiolasGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Fotis KothonasGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Georgios MargantinisGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Georgios KoukoulisGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.
Henry Dunant Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent meta-analyses have studied population differences concerning

methodsExtensive English language medical literature searches for human studies were performed up to the end of May 2013, using suitable keywords. Pooled estimates [odds ratio (OR) with 95% confidence intervals (CI)] were obtained using the random-effects model. Heterogeneity between studies was evaluated with the Cochran Q test whereas the likelihood of publication bias was assessed by constructing funnel plots. Their symmetry was estimated by the adjusted rank correlation test.

resultsIn seventeen studies, from various countries, the

conclusionIn this meta-analysis there was an overall statistically significant increased cancer risk associated with

Indexed as

gastric cancermeta-analysispolymorphismTNF-α-238 geneTNF-α-308 gene

Identifiers

PMID24733020
PMCPMC3982629
OpenAlexW2169770035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.