Evidence map›Paper›PMID 24732823›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2014

Burden of HIV infection among children aged 18 months to 14 years in Kenya: results from a nationally representative population-based cross-sectional survey.

Bernadette Ng'eno, Ann Mwangi, Lucy Ng'ang'a, Andrea A Kim, Anthony Waruru, Irene Mukui, Evelyn W Ngugi, George W Rutherford, KAIS Study Group

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
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  11. Disclosure and Clinical Outcomes Among Young Adolescents Living With HIV in Kenya.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019
    Article
  12. Article
  13. Using Observational Data to Inform HIV Policy Change for Children and Youth.Journal of acquired immune deficiency syndromes (1999) · 2018
    Observational
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bernadette Ng'eno*Division of Global HIV/AIDS, Center for Global Health, US Centers for Disease Control and Prevention, Nairobi, Kenya; †National AIDS and Sexually Transmitted Infection (STI) Control Programme, Ministry of Health, Nairobi, Kenya; and ‡Global Health Sciences, University of California, San Francisco, San Francisco, CA.
Ann Mwangi
Lucy Ng'ang'a
Andrea A Kim
Anthony Waruru
Irene Mukui
Evelyn W Ngugi
George W Rutherford
KAIS Study Group

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
CGH CDC HHS U19 GH000069Intramural CDC HHS CC999999NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

backgroundIn Kenya, mathematical models estimate that there are approximately 220,000 children aged less than 15 years infected with HIV. We analyzed data from the second Kenya AIDS Indicator Survey (KAIS 2012) to estimate the prevalence of HIV infection among children aged 18 months to 14 years.

methodsKAIS 2012 was a nationally representative 2-stage cluster sample household survey. We studied children aged 18 months to 14 years whose parents or guardians answered questions pertaining to their children by interview. Blood specimens were collected for HIV serology and viral load measurement.

resultsWe identified 5162 children who were eligible for the study. Blood was obtained for 3681 (71.3%) children. Among child participants, 16.4% had been tested for HIV infection in the past, and among children with parents or guardians who self-reported HIV-positive status, 52.9% had been tested for HIV infection. Twenty-eight (0.9%) children tested HIV-positive in the survey. Of these, 11 had been previously diagnosed with HIV infection before the survey. All 11 children were in HIV care and receiving cotrimoxazole; 8 were on antiretorivral therapy (ART). Among those on ART, 4 were virologically suppressed.

conclusionsHIV causes a substantial burden of disease in the Kenyan pediatric population. Although most children who had been diagnosed with HIV before the survey were engaged in care and treatment, they represented less than half of HIV-infected children identified in the survey. Future efforts should focus on identifying infected children and getting them into care and on suppressive ART as early as possible.

Indexed as

AdolescentAge FactorsAIDS SerodiagnosisAnti-Infective AgentsAnti-Retroviral AgentsChildChild, PreschoolCross-Sectional StudiesFemaleHealth SurveysHIV InfectionsHumansInfantKenyaMalePrevalenceAnti-Infective AgentsAnti-Retroviral AgentsTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID24732823
PMCPMC4784690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.