ReviewPlastic and reconstructive surgery2014
The role of stem cells in aesthetic surgery: fact or fiction?
Review in Plastic and reconstructive surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Non-enzymatic methods for isolation of stromal vascular fraction and adipose-derived stem cells: A systematic review.World journal of methodology · 2024Article
- Stem cells in plastic surgery and aesthetic medicine.Postepy dermatologii i alergologii · 2023Review
- The 50 most cited articles and science mapping analysis of vaginal tightening.International urogynecology journal · 2023Article
- Fat Grafts Augmented With Vitamin E Improve Volume Retention and Radiation-Induced Fibrosis.Aesthetic surgery journal · 2022Article
- Stem Cell Aging and Regenerative Medicine.Advances in experimental medicine and biology · 2021Review
- Biological Products: Cellular Therapy and FDA Approved Products.Stem cell reviews and reports · 2019Review
- The use of stem cells in aesthetic dermatology and plastic surgery procedures. A compact review of experimental and clinical applications.Postepy dermatologii i alergologii · 2017Article
- Regulated and Unregulated Clinical Trials of Stem Cell Therapies for Stroke.Translational stroke research · 2017Article
- Adipose-derived stem cells for breast reconstruction after breast surgery - preliminary results.Case reports in plastic surgery & hand surgery · 2017Article
- Shift toward Mechanical Isolation of Adipose-derived Stromal Vascular Fraction: Review of Upcoming Techniques.Plastic and reconstructive surgery. Global open · 2016Article
- Acceleration of osteogenesis by platelet-rich plasma with acellular dermal matrix in a calvarial defect model.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Breast Augmentation by Water-Jet Assisted Autologous Fat Grafting: A Report of 300 Operations.Surgery journal (New York, N.Y.) · 2016Article
- The Effect of Adipose-Derived Stem Cells on Full-Thickness Skin Grafts.BioMed research international · 2016Article
- Fat Grafting to the Forehead/Glabella/Radix Complex and Pyriform Aperture: Aesthetic and Anti-Aging Implications.Plastic and reconstructive surgery. Global open · 2015Article
- Cell-assisted lipotransfer.Deutsches Arzteblatt international · 2015Article
- [Regenerative therapy approaches in plastic surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2015Review
- Mesenchymal Stem Cells and Cutaneous Wound Healing: Current Evidence and Future Potential.Stem cells international · 2015Review
- Stem cell and research in plastic surgery.Journal of Korean medical science · 2014Review
Corrections and comments
- Commented on by
Authors and funding
10 authors at 1 institution in 3 countries.
Funding
Abstract
backgroundStem cells are attractive candidates for the development of novel therapies, targeting indications that involve functional restoration of defective tissue. Although most stem cell therapies are new and highly experimental, there are clinics around the world that exploit vulnerable patients with the hope of offering supposed stem cell therapies, many of which operate without credible scientific merit, oversight, or other patient protection.
methodsThe authors review the potential and the drawbacks of incorporation of stem cells in cosmetic procedures. A review of U.S. Food and Drug Administration-approved indications and ongoing clinical trials with adipose stem cells is provided. Furthermore, a "snapshot" analysis of Web sites using the search terms "stem cell therapy" or "stem cell treatment" or "stem cell facelift" was performed.
resultsDespite the protective net cast by regulatory agencies such as the U.S. Food and Drug Administration and professional societies such as the American Society of Plastic Surgeons, the authors are witnessing worrying advertisements for procedures such as stem cell face lifts, stem cell breast augmentations, and even stem cell vaginal rejuvenation. The marketing and promotion of stem cell procedures in aesthetic surgery is not adequately supported by clinical evidence in the majority of cases.
conclusionsStem cells offer tremendous potential, but the marketplace is saturated with unsubstantiated and sometimes fraudulent claims that may place patients at risk. With plastic surgeons at the forefront of stem cell-based regenerative medicine, it is critically important that they provide an example of a rigorous approach to research, data collection, and advertising of stem cell therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.