ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2014
Predicting persistence of functional abdominal pain from childhood into young adulthood.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Psychological therapies for the management of chronic and recurrent pain in children and adolescents.The Cochrane database of systematic reviews · 2018Pooled it
- Dietary interventions for recurrent abdominal pain in childhood.The Cochrane database of systematic reviews · 2017Pooled it
- The Role of Psychosocial Risk Status in Relation to Outcomes Following Cognitive Behavioral Therapy for Youth with Abdominal Pain-Related Disorders of Gut-Brain Interaction.Journal of clinical psychology in medical settings · 2026Trial
- Trial
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- Identifying Prognostic Factors Implicated in Chronic Functional Abdominal Pain in Children: A Systematic Review.Gastroenterology research · 2026Review
- A Dance and Yoga Intervention for Girls with Functional Abdominal Pain: Effects on Pain Frequency, Depressive Symptoms, Quality of Life, School Absenteeism, and Somatic Symptoms: A Randomized Controlled Trial.Children (Basel, Switzerland) · 2026Article
- Adult Rome IV Disorders of Gut-Brain Interaction in a Pediatric Population.Children (Basel, Switzerland) · 2026Article
- Longitudinal Association Between Bullying Victimization and Pediatric Functional Gastrointestinal Disorders (FGIDs) in Chinese Adolescents: Trajectories and Bidirectional Associations.Research on child and adolescent psychopathology · 2026Article
- Multimodal hypersensitivity and somatic symptoms predict adolescent postmenarchal widespread pain.Pain · 2025Article
- Risk Factors for Transition of Care in Disorders of Gut-Brain Interaction: A Narrative Review and Expert Opinion.Children (Basel, Switzerland) · 2025Review
- Repeat round of auricular percutaneous electrical nerve field stimulation for pediatric disorders of gut brain interaction.Journal of pediatric gastroenterology and nutrition · 2025Article
- Article
- Comparing the treatment effects of online cognitive-behavioral therapy for pediatric functional abdominal pain disorders with and without psychiatric comorbidity.Therapeutic advances in gastroenterology · 2025Article
- Pediatric to adult transition care in neurogastroenterology and motility: A position paper from the American Neurogastroenterology and Motility Society and European Society of Neurogastroenterology and Motility.Neurogastroenterology and motility · 2024Review
- Navigating through 65 years of insights: lessons learned on functional abdominal pain in children.European journal of pediatrics · 2024Review
- Frequency of Irritable Bowel Syndrome Among Children Aged 4 to 9 Years: A Cross-Sectional Study.Clinical pediatrics · 2024Article
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- Exploring Referral and Service Utilization Patterns Within an Outpatient Interdisciplinary Pediatric Chronic Pain Program.Journal of pain research · 2024Article
- ESPGHAN and NASPGHAN 2023 protocol for paediatric FAPD treatment guidelines (standard operating procedure).BMJ paediatrics open · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsPediatric functional abdominal pain has been linked to functional gastrointestinal disorders (FGIDs) in adulthood, but little is known about patient characteristics in childhood that increase the risk for FGID in young adulthood. We investigated the contribution of gastrointestinal symptoms, extraintestinal somatic symptoms, and depressive symptoms in pediatric patients with functional abdominal pain and whether these predicted FGIDs later in life.
methodsIn a longitudinal study, consecutive new pediatric patients, diagnosed with functional abdominal pain in a subspecialty clinic, completed a comprehensive baseline evaluation of the severity of their physical and emotional symptoms. They were contacted 5 to 15 years later and evaluated, based on Rome III symptom criteria, for abdominal pain-related FGIDs, including irritable bowel syndrome, functional dyspepsia, functional abdominal pain syndrome, and abdominal migraine. Controlling for age, sex, baseline severity of abdominal pain, and time to follow-up evaluation, multivariable logistic regression was used to evaluate the association of baseline gastrointestinal, extraintestinal somatic, and depressive symptoms in childhood with FGID in adolescence and young adulthood.
resultsOf 392 patients interviewed an average of 9.2 years after their initial evaluation, 41% (n = 162) met symptom criteria for FGID; most met the criteria for irritable bowel syndrome. Extraintestinal somatic and depressive symptoms at the initial pediatric evaluation were significant predictors of FGID later in life, after controlling for initial levels of GI symptoms. Age, sex, and abdominal pain severity at initial presentation were not significant predictors of FGID later in life.
conclusionsIn pediatric patients with functional abdominal pain, assessment of extraintestinal and depressive symptoms may be useful in identifying those at risk for FGID in adolescence and young adulthood.
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