Evidence map›Paper›PMID 24732161›Full record

ReviewTobacco control2014

Electronic cigarettes: human health effects.

Priscilla Callahan-Lyon

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Tobacco control, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04982978 (The Effectiveness of the Protection Motivation Theory in Reducing Vaping Behaviour in a Student Population), which is not on this map. Cited by 201 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed, 4 pooled it
27.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04982978 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effectiveness of the Protection Motivation Theory in Reducing Vaping Behaviour in a Student Population

TypeinterventionalSponsorWestern UniversityRan2021 to 2021Enrolled77ConditionsVaping Related DisorderArmsPMT Threat Appraisal, General Nutrition and Lifestyle
3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 4 syntheses or guidelines pooled it, 456 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Overview of Electronic Nicotine Delivery Systems: A Systematic Review.American journal of preventive medicine · 2017
    Pooled it
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141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Priscilla Callahan-Lyon
Office of Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWith the rapid increase in use of electronic nicotine delivery systems (ENDS), such as electronic cigarettes (e-cigarettes), users and non-users are exposed to the aerosol and product constituents. This is a review of published data on the human health effects of exposure to e-cigarettes and their components.

methodsLiterature searches were conducted through September 2013 using multiple electronic databases.

resultsForty-four articles are included in this analysis. E-cigarette aerosols may contain propylene glycol, glycerol, flavourings, other chemicals and, usually, nicotine. Aerosolised propylene glycol and glycerol produce mouth and throat irritation and dry cough. No data on the effects of flavouring inhalation were identified. Data on short-term health effects are limited and there are no adequate data on long-term effects. Aerosol exposure may be associated with respiratory function impairment, and serum cotinine levels are similar to those in traditional cigarette smokers. The high nicotine concentrations of some products increase exposure risks for non-users, particularly children. The dangers of secondhand and thirdhand aerosol exposure have not been thoroughly evaluated.

conclusionsScientific evidence regarding the human health effects of e-cigarettes is limited. While e-cigarette aerosol may contain fewer toxicants than cigarette smoke, studies evaluating whether e-cigarettes are less harmful than cigarettes are inconclusive. Some evidence suggests that e-cigarette use may facilitate smoking cessation, but definitive data are lacking. No e-cigarette has been approved by FDA as a cessation aid. Environmental concerns and issues regarding non-user exposure exist. The health impact of e-cigarettes, for users and the public, cannot be determined with currently available data.

Indexed as

AerosolsCotinineElectronic Nicotine Delivery SystemsEnvironmental ExposureGlycerolHumansNicotineAerosolsCotinineGlycerolNicotineadverse eventaerosole-cigarettessecond-hand exposuretoxicity

Identifiers

PMID24732161
PMCPMC3995250
OpenAlexW2144345975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.