Trial reportActa veterinaria Scandinavica2014
Effects of Artemisia annua and Foeniculum vulgare on chickens highly infected with Eimeria tenella (phylum Apicomplexa).
Trial report in Acta veterinaria Scandinavica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 55 citations in OpenAlex.
- Anticoccidial effects of Artemisia annua ethanolic extract: prevention, simultaneous challenge-medication, and treatment.Parasitology research · 2017Trial
- Evaluation of natural plant extracts as alternatives to chemical antiparasitics inOpen veterinary journal · 2026Article
- Insights into Non-Antibiotic Alternative and Emerging Control Strategies for Chicken Coccidiosis.Animals : an open access journal from MDPI · 2026Review
- The Beneficial Use ofAnimals : an open access journal from MDPI · 2025Review
- Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs.BMC veterinary research · 2025Article
- Article
- Comparative analysis of pathogenicity and anticoccidial resistance of field-isolatedFrontiers in veterinary science · 2025Article
- Oral vaccination with a recombinant Lactobacillus plantarum expressing the Eimeria tenella rhoptry neck 2 protein elicits protective immunity in broiler chickens infected with Eimeria tenella.Parasites & vectors · 2024Article
- Coccidiosis in Egg-Laying Hens and Potential Nutritional Strategies to Modulate Performance, Gut Health, and Immune Response.Animals : an open access journal from MDPI · 2024Review
- Effects ofFrontiers in physiology · 2024Article
- Nutritional interventions to support broiler chickens during Eimeria infection.Poultry science · 2022Article
- Phytochemical control of poultry coccidiosis: a review.Poultry science · 2022Review
- Essential Oil Delivery Route: Effect on Broiler Chicken's Growth Performance, Blood Biochemistry, Intestinal Morphology, Immune, and Antioxidant Status.Animals : an open access journal from MDPI · 2021Article
- Fennel affects ovarian cell proliferation, apoptosis, and response to ghrelin.Physiological research · 2021Article
- Experimental infection with Toxoplasma gondii in broiler chickens (Gallus domesticus): seroconversion, tissue cyst distribution, and prophylaxis.Parasitology research · 2021Article
- Helminthiases; prevalence, transmission, host-parasite interactions, resistance to common synthetic drugs and treatment.Heliyon · 2019Review
- Diagnosis and control of chicken coccidiosis: a recent update.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018Review
- Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review.Parasites & vectors · 2018Review
- Systematic Review of Phytotherapeutic Treatments for Different Farm Animals Under European Conditions.Frontiers in veterinary science · 2018Article
- Anticoccidial effects of herbal extracts on Eimeria tenella infection in broiler chickens: in vitro and in vivo study.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive poultry production systems depend on chemoprophylaxis with anticoccidial drugs to combat infection. A floor-pen study was conducted to evaluate the anticoccidial effect of Artemisia annua and Foeniculum vulgare on Eimeria tenella infection. Five experimental groups were established: negative control (untreated, unchallenged); positive control (untreated, challenged); a group medicated with 125 ppm lasalocid and challenged; a group medicated with A. annua leaf powder at 1.5% in feed and challenged; and a group treated with the mixed oils of A. annua and Foeniculum vulgare in equal parts, 7.5% in water and challenged. The effects of A. annua and oil extract of A. annua + F. vulgare on E. tenella infection were assessed by clinical signs, mortality, fecal oocyst output, faeces, lesion score, weight gain, and feed conversion.
resultsClinical signs were noticed only in three chickens from the lasalocid group, six from the A. annua group, and nine from the A. annua + F. vulgare group, but were present in 19 infected chickens from the positive control group. Bloody diarrhea was registered in only two chickens from A. annua group, but in 17 chickens from the positive control group. Mortality also occurred in the positive control group (7/20). Chickens treated with A. annua had a significant reduction in faecal oocysts (95.6%; P = 0.027) and in lesion score (56.3%; P = 0.005) when compared to the positive control. At the end of experiment, chickens treated with A. annua leaf powder had the highest body weight gain (68.2 g/day), after the negative control group, and the best feed conversion (1.85) among all experimental groups.
conclusionsOur results suggest that A. annua leaf powder (Aa-p), at 1.5% of the daily diet post-infection, can be a valuable alternative for synthetic coccidiostats, such as lasalocid.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.