ArticleThe journal of physical chemistry. B2014
Multidimensional mapping of spin-exchange optical pumping in clinical-scale batch-mode 129Xe hyperpolarizers.
Article in The journal of physical chemistry. B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Hyperpolarised magnetic resonance spectroscopy with lab-on-a-chip disease models.Disease models & mechanisms · 2026Review
- Detection of the Carcinogen Benzo[Analytical chemistry · 2026Article
- Continuous Delivery of Hyperpolarized Xenon-129 Gas Using a "Stopped-Flow" Clinical-Scale Cryogen-Free Hyperpolarizer.Analytical chemistry · 2025Article
- Article
- Pilot Quality-Assurance Study of a Third-Generation Batch-Mode Clinical-Scale Automated Xenon-129 Hyperpolarizer.Molecules (Basel, Switzerland) · 2022Article
- Enabling Clinical Technologies for HyperpolarizedAngewandte Chemie (International ed. in English) · 2021Review
- Hyperpolarised gas filling station for medical imaging using polarisedMagnetic resonance imaging · 2021Article
- High Xe density, high photon flux, stopped-flow spin-exchange optical pumping: Simulations versus experiments.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020Article
- Clinical-Scale Batch-Mode Production of Hyperpolarized Propane Gas for MRI.Analytical chemistry · 2019Article
- Heterogeneous Parahydrogen Pairwise Addition to Cyclopropane.Chemphyschem : a European journal of chemical physics and physical chemistry · 2018Article
- Quasi-Resonance Signal Amplification by Reversible Exchange.The journal of physical chemistry letters · 2018Article
- A pulse programmable parahydrogen polarizer using a tunable electromagnet and dual channel NMR spectrometer.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- High-resolution hyperpolarized in vivo metabolicJournal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- Depolarization of nuclear spin polarizedJournal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- NMR Spin-Lock Induced Crossing (SLIC) dispersion and long-lived spin states of gaseous propane at low magnetic field (0.05T).Journal of magnetic resonance (San Diego, Calif. : 1997) · 2017Article
- Open-Source Automated Parahydrogen Hyperpolarizer for Molecular Imaging Using (13)C Metabolic Contrast Agents.Analytical chemistry · 2016Article
- NMR hyperpolarization techniques for biomedicine.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015Article
- Propane-The journal of physical chemistry. C, Nanomaterials and interfaces · 2014Article
- Temperature-ramped (129)Xe spin-exchange optical pumping.Analytical chemistry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
We present a systematic, multiparameter study of Rb/(129)Xe spin-exchange optical pumping (SEOP) in the regimes of high xenon pressure and photon flux using a 3D-printed, clinical-scale stopped-flow hyperpolarizer. In situ NMR detection was used to study the dynamics of (129)Xe polarization as a function of SEOP-cell operating temperature, photon flux, and xenon partial pressure to maximize (129)Xe polarization (PXe). PXe values of 95 ± 9%, 73 ± 4%, 60 ± 2%, 41 ± 1%, and 31 ± 1% at 275, 515, 1000, 1500, and 2000 Torr Xe partial pressure were achieved. These PXe polarization values were separately validated by ejecting the hyperpolarized (129)Xe gas and performing low-field MRI at 47.5 mT. It is shown that PXe in this high-pressure regime can be increased beyond already record levels with higher photon flux and better SEOP thermal management, as well as optimization of the polarization dynamics, pointing the way to further improvements in hyperpolarized (129)Xe production efficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.