Evidence map›Paper›PMID 24730413›Full record

GuidelineAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2014

A consensus parameter for the evaluation and management of angioedema in the emergency department.

Joseph J Moellman, Jonathan A Bernstein, Christopher Lindsell, Aleena Banerji, Paula J Busse, Carlos A Camargo, Sean P Collins, Timothy J Craig, William R Lumry, Richard Nowak and 12 more

2 registry-linked trialsOpen access · bronzeAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06096077 completednot on this mapstarted 2022, after this paper: background citation

Evaluation of Tranexamic Acid for Angiotensin-converting Enzyme Inhibitor-induced Angioedema in the Emergency Department

TypeobservationalSponsorMethodist Health SystemRan2022 to 2023Enrolled50ConditionsAngioedema
NCT06679426 phase3unknown statusnot on this mapstarted 2024, after this paper: background citation

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Study Evaluating the Safety and Efficacy of Conestat Alfa As a Treatment for Angiotensin-Converting Enzyme-Inhibitor-Induced Angioedema

TypeinterventionalSponsorUniversity of CincinnatiRan2024 to 2025Enrolled24ConditionsACE Inhibitor-Induced AngioedemaArmsConestat Alfa
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 136 citations in OpenAlex.

  1. Trial
  2. [What are angioedemas and how are they classified?]Dermatologie (Heidelberg, Germany) · 2026
    Review
  3. Airway Intervention in Paediatric Angioedema: A National Analysis of Clinical Predictors and Outcomes.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Article
  4. Medical Malpractice in the Management of Angioedema: A Multidisciplinary Westlaw Analysis.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  5. Article
  6. The International/Canadian hereditary angioedema guideline.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Bradykinin Metabolism and Drug-Induced Angioedema.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Review
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 11 institutions in 1 country.

Joseph J MoellmanThe Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.
Jonathan A Bernstein
Christopher Lindsell
Aleena Banerji
Paula J Busse
Carlos A Camargo
Sean P Collins
Timothy J Craig
William R Lumry
Richard Nowak
Jesse M Pines
Ali S Raja
Marc Riedl
Michael J Ward
Bruce L Zuraw
Deborah Diercks
Brian Hiestand
Ronna L Campbell
Sandra Schneider
Richard Sinert
American College of Allergy, Asthma & Immunology (ACAAI)
Society for Academic Emergency Medicine (SAEM)
University of Cincinnati Medical Center · USMassachusetts General Hospital · USVanderbilt University · USAsthma and Allergy Specialists · USBrigham and Women's Hospital · USGeorge Washington University · USHenry Ford Health System · USMount Sinai Hospital · USPenn State Milton S. Hershey Medical Center · USUniversity of California, Los Angeles · USUniversity of California, San Diego · US

Funding

The Vanderbilt Emergency Medicine Research Training Program (VEMRT)K12HL109019 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COLLINS, SEAN PATRICK, STORROW, ALAN B · 2011 to 2015
$3.7M
Treatment Endpoints in Acute Decompensated Heart FailureK23HL085387 · NHLBI · VANDERBILT UNIVERSITY · PI COLLINS, SEAN PATRICK · 2008 to 2012
$797k
NHLBI NIH HHS K12 HL109019NHLBI NIH HHS K23 HL085387
6 · The paper itself

Abstract

Despite its relatively common occurrence and life-threatening potential, the management of angioedema in the emergency department (ED) is lacking in terms of a structured approach. It is paramount to distinguish the different etiologies of angioedema from one another and more specifically differentiate histaminergic-mediated angioedema from bradykinin-mediated angioedema, especially in lieu of the more novel treatments that have recently become available for bradykinin-mediated angioedema. With this background in mind, this consensus parameter for the evaluation and management of angioedema attempts to provide a working framework for emergency physicians (EPs) in approaching the patient with angioedema in terms of diagnosis and management in the ED. This consensus parameter was developed from a collaborative effort among a group of EPs and leading allergists with expertise in angioedema. After rigorous debate, review of the literature, and expert opinion, the following consensus guideline document was created. The document has been endorsed by the American College of Allergy, Asthma & Immunology (ACAAI) and the Society for Academic Emergency Medicine (SAEM).

Indexed as

Emergency Service, HospitalAirway ManagementAngioedemaCardiovascular AgentsHospitalizationHumansUnited StatesCardiovascular Agents

Identifiers

PMID24730413
PMCPMC4100605
OpenAlexW2070119625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.