Evidence map›Paper›PMID 24729910›Full record

ArticleParkinson's disease2014

Trends in antiparkinsonian medication use in new zealand: 1995-2011.

T L Pitcher, M R Macaskill, T J Anderson

Abstract read
In one paragraph

Article in Parkinson's disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Amantadine-induced corneal edema: A case and literature review.American journal of ophthalmology case reports · 2023
    Article
  3. Article
  4. Article
  5. Factors affecting the choice of first-line therapy in Parkinson's disease patients in Wales: A population-based study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T L PitcherDepartment of Medicine, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand ; New Zealand Brain Research Institute, 66 Stewart Street, Christchurch 8011, New Zealand.
M R MacaskillDepartment of Medicine, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand ; New Zealand Brain Research Institute, 66 Stewart Street, Christchurch 8011, New Zealand.
T J AndersonDepartment of Medicine, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand ; New Zealand Brain Research Institute, 66 Stewart Street, Christchurch 8011, New Zealand ; Department of Neurology, Canterbury District Health Board, Private Bag 4710, Christchurch 8140, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prescribing trends for medications are influenced by development of new drugs, changes in knowledge about efficacy and side effects, and priorities set by funding agencies. Changes in the utilization of antiparkinsonian agents in the outpatient community in New Zealand were investigated by using the national prescription database for the period 1995-2011. The dispensed volumes of antiparkinsonian agents were converted into number of defined daily doses per 1000 inhabitants per day for analysis. Increases in the dispensed volumes of levodopa (77%), amantadine (350%), and catechol-o-methyl transferase inhibitors (326%) occurred during the study period. Conversely, decreases in the dispensed volumes of anticholinergics (48%), selegiline (82%), and dopamine agonists (6.2%) were observed. New Zealand has seen a substantial increase of the amount of levodopa dispensed in the past 17 years. This increase appears to be related to an increase in the number of people taking the medication. We are unable to extrapolate this change to an increase in the prevalence of PD, given levodopa is used in the treatment of a number of medical conditions. The changes in other antiparkinsonian medications largely reflect changes in availability (increases in entacapone and ropinirole) and best practice treatment (declines in anticholinergics, selegiline, and tolcapone).

Identifiers

PMID24729910
PMCPMC3960778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.