Evidence map›Paper›PMID 24729878›Full record

ReviewISRN gastroenterology2014

Epigenetic biomarkers: potential applications in gastrointestinal cancers.

Jiaqiu Li, Hongchuan Jin, Xian Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ISRN gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. DNA methylation status defines clinicopathological parameters including survival for patients with clear cell renal cell carcinoma (ccRCC).Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  5. Article
  6. Review
  7. Challenges of deciphering gastric cancer heterogeneity.World journal of gastroenterology · 2015
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiaqiu LiDepartment of Medical Oncology, Sir Runrun Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310016, China.
Hongchuan JinDepartment of Medical Oncology, Sir Runrun Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310016, China.ORCID 0000-0002-6697-3097
Xian WangDepartment of Medical Oncology, Sir Runrun Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetics and epigenetics coregulate the cancer initiation and progression. Epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, and noncoding RNAs. Aberrant epigenetic modifications play a fundamental role in the formation of gastrointestinal cancers. Advances in epigenetics offer a better understanding of the carcinogenesis and provide new insights into the discovery of biomarkers for diagnosis, and prognosis prediction of human cancers. This review aims to overview the epigenetic aberrance and the clinical applications as biomarkers in gastrointestinal cancers mainly gastric cancer and colorectal cancer.

Identifiers

PMID24729878
PMCPMC3963109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.