ArticleJournal of diabetes investigation2014
Potential association between prediabetic conditions and gingival and/or periodontal inflammation.
Article in Journal of diabetes investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Association between prediabetes and periodontitis: a meta-analysis of observational studies with multivariate analysis.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Does Periodontal Inflammation Affect Type 1 Diabetes in Childhood and Adolescence? A Meta-Analysis.Frontiers in endocrinology · 2020Pooled it
- Salivary biomarker profiling in prediabetes-associated periodontitis: role of adiponectin, resistin, and total matrix metalloproteinase-8.Frontiers in dental medicine · 2026Article
- Oral Inflammation and Human Papilloma Virus Association among Hispanics.International journal of dentistry · 2023Article
- Referral Compliance Following a Diabetes Screening in a Dental Setting: A Scoping Review.Healthcare (Basel, Switzerland) · 2022Article
- The relationship between inflammatory dietary pattern and incidence of periodontitis.The British journal of nutrition · 2021Article
- Insulin resistance predicts the risk of gingival/periodontal inflammation.Journal of periodontology · 2018Article
- Article
- Cross-sectional associations of impaired glucose metabolism measures with bleeding on probing and periodontitis.Journal of clinical periodontology · 2017Article
- Relationship between periodontal disease and asthma among overweight/obese adults.Journal of clinical periodontology · 2016Article
- Neutrophil Functions in Periodontal Homeostasis.Journal of immunology research · 2016Review
- Lipid-lowering agents use and systemic and oral inflammation in overweight or obese adult Puerto Ricans: the San Juan Overweight Adults Longitudinal Study (SOALS).Journal of clinical periodontology · 2015Article
- Management of periodontal disease in patients with diabetes- good clinical practice guidelines: A joint statement by Indian Society of Periodontology and Research Society for the Study of Diabetes in India.Journal of Indian Society of PeriodontologyArticle
- A pilot study on glycemia and insulin resistance in patients with severe periodontitis.Journal of Indian Society of PeriodontologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
AIMS/
introductionPrediabetic conditions, which include impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), might be associated with chronic gingival and/or periodontal inflammation. However, the occurrence of this oral inflammation in prediabetic conditions is poorly understood. The present study aimed to assess the association between prediabetes and gingival and/or periodontal inflammation. MATERIALS AND
methodsA total of 94 Puerto Rican men and women aged 40-65 years, who were residents of San Juan, Puerto Rico, and free of diabetes, were included in the study. All participants had at least one tooth site with clinical attachment loss ≥3 mm. Fasting and 2-h plasma glucose were collected. Gingival/periodontal inflammation was assessed by bleeding on gentle probing of the sulcus at six sites per tooth.
resultsParticipants with the percentage of teeth with bleeding on probing (BOP) equal to or greater than the median were compared with those with the percentage of teeth with BOP less than median. Participants with high BOP tended to present higher IFG (odds ratio [OR] 5.5, 95% confidence interval [CI] 1.2-25.3) and/or prediabetic condition (OR 3.6, 95% CI 1.0-13.2) than those with a low percentage of BOP, adjusting for age, sex, smoking, alcohol consumption, waist circumference and number of missing teeth. Using the continuous form of the outcome, the corresponding adjusted least squares means of percentage of BOP were 26.8 (standard error of the mean [SEM] 2.3) and 43.8 (SEM 6.0) in normal and IFG, respectively (
conclusionIFG and/or prediabetes are strongly associated with BOP, a marker of chronic gingival/periodontal inflammation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.