Evidence map›Paper›PMID 24729813›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2014

Surgical management of gastrointestinal stromal tumors: a single center experience.

Eligijus Poškus, Pavel Petrik, Eglė Petrik, Vytautas Lipnickas, Juozas Stanaitis, Kęstutis Strupas

Registry-linked trialAbstract read
In one paragraph

Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03716089 (Prospective Controlled Clinical Trial for Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site(FUGES-016)), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03716089 recruitingnot on this mapstarted 2018, after this paper: background citation

Prospective Controlled Clinical Trial for Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site(FUGES-016)

TypeobservationalSponsorFujian Medical UniversityRan2018 to 2027Enrolled250ConditionsGIST of Stomach, Gastric Cancer, Surgery, ComplicationArmsLaparoscopic resection
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Laparoscopic removal of gastrointestinal stromal tumors of uncinate process of pancreas.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2015
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eligijus PoškusClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.
Pavel PetrikClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.
Eglė PetrikDepartment of Physiology, Biochemistry and Laboratory Medicine, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.
Vytautas LipnickasClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.
Juozas StanaitisClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.
Kęstutis StrupasClinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Vilnius University, Faculty of Medicine, Vilnius, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. Although the therapy targeted at inhibiting tyrosine kinases has shown dramatic results in metastatic and inoperable GISTs, the mainstay of treatment in primary localized forms remains surgical resection.

aimTo provide an overview of our experience of GIST diagnosis and management, with emphasis on comparison of minimally invasive and open surgical resection for primary GISTs. MATERIAL AND

methodsWe retrospectively reviewed the medical records of all patients who underwent surgical removal of GISTs from 2008 to 2012. Patient demographics, clinical data, surgery, complications, histopathological data and clinical course were analyzed.

resultsForty-four patients were identified. Average age at diagnosis was 63 years. Minimally invasive (MIS) and open surgery (OS) were each attempted in 22 (50.0%) patients. Laparoscopic removal was performed in 20, laparoendoscopic in 1, and laparoscopy-assisted endoscopic removal in 1. Conversion to an open procedure was performed in 4 (18.2%). We found significant differences in postoperative length of stay (8.5 days vs. 10.1 days, p < 0.001) and tumor size (2.93 cm vs. 5.78 cm, p = 0.018) between MIS and OS groups, respectively.

conclusionsLaparoscopic removal is safe and effective for GISTs not exceeding 6 cm. Gastroesophageal junction and cardia GISTs require careful preoperative evaluation and planning to remove safely. We recommend avoiding laparoscopic removal of these tumors due to the high rate of conversion (100.0%) to an open procedure. Laparoendoscopic surgical approach is an appropriate technique for removal of small-sized intraluminal benign GISTs not involving the muscularis propria layer.

Indexed as

gastrointestinal stromal tumorsminimally invasive surgery

Identifiers

PMID24729813
PMCPMC3983553

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.