Evidence map›Paper›PMID 24729793›Full record

ArticleMental health and physical activity2014

A Health Education Intervention as the Control Condition in the CTN-0037 STRIDE multi-site exercise trial: Rationale and Description.

Chad D Rethorst, Tracy L Greer, Bruce Grannemann, Kolette M Ring, Bess H Marcus, Madhukar H Trivedi

Abstract read
In one paragraph

Article in Mental health and physical activity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic review of control groups in nutrition education intervention research.The international journal of behavioral nutrition and physical activity · 2017
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chad D RethorstDepartment of Psychiatry, University of Texas Southwestern Medical Center.
Tracy L GreerDepartment of Psychiatry, University of Texas Southwestern Medical Center.
Bruce GrannemannDepartment of Psychiatry, University of Texas Southwestern Medical Center.
Kolette M RingDepartment of Psychiatry, University of Texas Southwestern Medical Center.
Bess H MarcusDepartment of Family and Preventive Medicine, University of California San Diego.
Madhukar H TrivediDepartment of Psychiatry, University of Texas Southwestern Medical Center.

Funding

Project-004UG1DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI Steven J Shoptaw, MADHUKAR H. TRIVEDI · 2015 to 2026
$71.6M
Concept ProjectU10DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI TRIVEDI, MADHUKAR H. · 2005 to 2015
$22.6M
An Exercise Intervention to Prevent Interferon-Induced Depression in Hepatitis CK01MH097847 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI RETHORST, CHAD D · 2013 to 2016
$595k
NIDA NIH HHS U10 DA020024NIDA NIH HHS UG1 DA020024NIMH NIH HHS K01 MH097847
6 · The paper itself

Abstract

The selection of a control condition in a randomized controlled trial (RCT) is critical in determining the effect of the experimental treatment. While the use of a placebo pill can be an ideal control in pharmaceutical trials, RCTs of behavioral interventions present unique challenges in the selection and implementation of the appropriate control condition. Investigators must not only consider the control condition's ability to protect against threats to internal validity and its plausibility as a possible intervention, but must also carefully implement the control condition so it does not introduce bias from either the investigators or the participants. The purpose of this paper is to provide the rationale for the use of a health education intervention (HEI) as the control condition in the CTN-0037 Stimulant Reduction Intervention Using Dosed Exercise (STRIDE) trial. In this paper, we will describe the careful design of the HEI to ensure proper implementation and discuss alternative control conditions considered.

Indexed as

Control conditionDesignExerciseHealth Education

Identifiers

PMID24729793
PMCPMC3979565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.