Evidence map›Paper›PMID 24729758›Full record

ArticleFocus (American Psychiatric Publishing)2013

Depression in Late-Life: a Focus on Prevention.

Olivia I Okereke, Jeffrey M Lyness, Francis E Lotrich, Charles F Reynolds

Abstract read
In one paragraph

Article in Focus (American Psychiatric Publishing), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Effects of Vitamin DThe Journal of clinical psychiatry · 2023
    Trial
  3. Trial
  4. Prevention of late-life depression: a framework and prospectus for research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  5. Public Health Perspectives of Geriatric Mental Health Care.Indian journal of psychological medicine · 2021
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Biological Aging and the Future of Geriatric Psychiatry.The journals of gerontology. Series A, Biological sciences and medical sciences · 2017
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Olivia I OkerekeChanning Division of Network Medicine (OIO), Department of Medicine, and Department of Psychiatry (OIO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Psychiatry (JML), University of Rochester School of Medicine & Dentistry, Rochester, NY, United States; University of Pittsburgh Medical Center (FEL), Pittsburgh, PA, United States; Department of Psychiatry (CFR), University of Pittsburgh School of Medicine, and Department of Behavioral and Community Health Sciences (CFR), Graduate School of Public Health, Pittsburgh, PA, United States.
Jeffrey M LynessChanning Division of Network Medicine (OIO), Department of Medicine, and Department of Psychiatry (OIO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Psychiatry (JML), University of Rochester School of Medicine & Dentistry, Rochester, NY, United States; University of Pittsburgh Medical Center (FEL), Pittsburgh, PA, United States; Department of Psychiatry (CFR), University of Pittsburgh School of Medicine, and Department of Behavioral and Community Health Sciences (CFR), Graduate School of Public Health, Pittsburgh, PA, United States.
Francis E LotrichChanning Division of Network Medicine (OIO), Department of Medicine, and Department of Psychiatry (OIO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Psychiatry (JML), University of Rochester School of Medicine & Dentistry, Rochester, NY, United States; University of Pittsburgh Medical Center (FEL), Pittsburgh, PA, United States; Department of Psychiatry (CFR), University of Pittsburgh School of Medicine, and Department of Behavioral and Community Health Sciences (CFR), Graduate School of Public Health, Pittsburgh, PA, United States.
Charles F ReynoldsChanning Division of Network Medicine (OIO), Department of Medicine, and Department of Psychiatry (OIO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States; Department of Psychiatry (JML), University of Rochester School of Medicine & Dentistry, Rochester, NY, United States; University of Pittsburgh Medical Center (FEL), Pittsburgh, PA, United States; Department of Psychiatry (CFR), University of Pittsburgh School of Medicine, and Department of Behavioral and Community Health Sciences (CFR), Graduate School of Public Health, Pittsburgh, PA, United States.
Brigham and Women's Hospital · USUniversity of Pittsburgh Medical Center · USUniversity of Rochester · US

Funding

RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F · 2011 to 2015
$8.3M
VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaLR01MH091448 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI OKEREKE, OLIVIA IFEOMA · 2010 to 2019
$6.5M
1/3-Incomplete Response in Late-Life Depression: Getting to RemissionR01MH083660 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2009 to 2013
$2.7M
Vulnerability to major depression: The role of delta sleep in patients receivingR01MH090250 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOTRICH, FRANCIS E · 2010 to 2014
$1.6M
VITAL-DEP (VITamin D and OmegA 3 TriaL-Depression Endpoint Prevention)R56MH091448 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI OKEREKE, OLIVIA IFEOMA · 2022 to 2022
$1.3M
NIMH NIH HHS P30 MH090333NIMH NIH HHS R01 MH083660NIMH NIH HHS R01 MH090250NIMH NIH HHS R01 MH091448NIMH NIH HHS R56 MH091448
6 · The paper itself

Abstract

Depression is a leading cause of disease burden, disability and distress for millions of older adults. Thus, prevention of late-life depression is a priority research area. This article addresses the science of late-life depression prevention with the following: 1) an introduction to the Institute of Medicine framework of universal, selective and indicated prevention as it pertains to late-life depression, with particular attention to successes of indicated and selective prevention in primary care; 2) a discussion of how biomarkers can be integrated into prevention research, using interferon-alpha-induced depression as a model; 3) an outline for expansion of prevention to non-specialist care delivery systems in Low and Middle Income Countries - thus, extending the reach of current successful approaches; 4) a description of a novel approach to simultaneous testing of universal, selective and indicated prevention in late-life depression, with emphasis on study design features required to achieve practical, scalable tests of health impact.

Identifiers

PMID24729758
PMCPMC3982610
OpenAlexW2140666862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.