Evidence map›Paper›PMID 24729698›Full record

SynthesisInternational journal of chronic obstructive pulmonary disease2014

Examining the relationship between anxiety and depression and exacerbations of COPD which result in hospital admission: a systematic review.

Alison Pooler, Roger Beech

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of chronic obstructive pulmonary disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04088942 (A Randomized Open-label, Superiority, Multicenter, Two-arm Intervention Study of the Effect of "High-intensity" vs. 'Low-intensity' Smoking Cessation Intervention in Active Smokers With COPD), which is not on this map. Cited by 87 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 7 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04088942 phase4withdrawnnot on this mapstarted 2023, after this paper: background citation

A Randomized Open-label, Superiority, Multicenter, Two-arm Intervention Study of the Effect of "High-intensity" vs. 'Low-intensity' Smoking Cessation Intervention in Active Smokers With COPD

TypeinterventionalSponsorPradeesh SivapalanRan2023 to 2026Enrolled0ConditionsChronic Obstructive Pulmonary Disease, Smoking Cessation, Lung Diseases, Obstructive, Pulmonary Disease, Chronic ObstructiveArmsHigh-intensity smoking cessation intervention, Low-intensity smoking cessation intervention
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 7 syntheses or guidelines pooled it, 193 citations in OpenAlex.

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  5. The frequent and underrecognised co-occurrence of acute exacerbated COPD and depression warrants screening: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2017
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alison PoolerSchool of Nursing and Midwifery, Clinical Education Centre, University Hospital of North Staffordshire NHS Trust, Stoke-on-Trent, UK ; Health Services Research, Research Institute of Primary Care and Health Sciences, Keele University, Keele, UK.
Roger BeechHealth Services Research, Research Institute of Primary Care and Health Sciences, Keele University, Keele, UK.
Keele University · GBUniversity Hospitals of North Midlands NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesExacerbations of chronic obstructive pulmonary disease (COPD) are the third largest cause of emergency hospital admissions in the UK. This systematic literature review explored the relationship between the hospitalization rates and the COPD comorbidities, anxiety, and depression.

methodsThe Centre for Research Dissemination's framework for systematic reviews was followed using search terms relating to COPD, anxiety, depression, and hospital admission. Papers identified were assessed for relevance and quality, using a suitable Critical Appraisal Skills Programme tool and Mixed Methods Assessment Tool.

resultsTwenty quantitative studies indicated that anxiety and depression led to a statistically significant increase in the likelihood of COPD patients being hospitalized. These comorbidities also led to an increased length of stay and a greater risk of mortality postdischarge. Other significant factors included lower Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise scores, female gender, lower socioeconomic status, poorer patient perceived quality of life, increased severity of lung function, and less improvement in dyspnea from admission to discharge. It was also highlighted that only 27%-33% of those with depression were being treated for it. Four qualitative studies revealed that patients saw anxiety and depression as a major factor that affected their ability to cope with and self-manage their condition. IMPLICATIONS: Findings from the systematic review have highlighted a need for better recognition and treatment of anxiety and depression amongst individuals with COPD. Ongoing research will develop and test strategies for promoting better management and self-management as a means of reducing hospital admissions.

Indexed as

Patient AdmissionAdaptation, PsychologicalAnxietyComorbidityDepressionDisease ProgressionHumansLungPatient ReadmissionPrognosisPulmonary Disease, Chronic ObstructiveRisk FactorsanxietyCOPDdepressionexacerbationshospital admissions

Identifiers

PMID24729698
PMCPMC3974694
OpenAlexW2073201370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.