ReviewClinical interventions in aging2014
Vitamin D and neurocognitive function.
Review in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02416193 (Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes?), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Associations of vitamin D receptor polymorphisms with risk of Alzheimer's disease, Parkinson's disease, and mild cognitive impairment: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2024Pooled it
- Vitamin D deficiency is associated with increased risk of Alzheimer's disease and dementia: evidence from meta-analysis.Nutrition journal · 2015Pooled it
- Trial
- Vitamin D Supplementation and Cognition in People with Type 2 Diabetes: A Randomized Control Trial.Journal of diabetes research · 2019Trial
- Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial.BMC geriatrics · 2015Trial
- Article
- Vitamin D and Older Adults: To Supplement or Not to Supplement?Drugs & aging · 2026Review
- Vitamin D and exercise in obesity: a neurovascular-muscle axis.Frontiers in nutrition · 2026Review
- Neuroprotective Roles of Vitamin D: Bridging the Gap Between Mechanisms and Clinical Applications in Cognitive Decline.International journal of molecular sciences · 2025Review
- Association between serum 25-hydroxyvitamin D3 level and cognitive impairment in older chronic kidney disease patients.Scientific reports · 2024Article
- Neuroimmunological Effect of Vitamin D on Neuropsychiatric Long COVID Syndrome: A Review.Nutrients · 2023Review
- Impact of Vitamin D Deficiency on Mental Health in University Students: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Vitamin D and neurodegenerative diseases.Heliyon · 2023Review
- Review
- Article
- The Role of Nutrients in Prevention, Treatment and Post-Coronavirus Disease-2019 (COVID-19).Nutrients · 2022Review
- Cognitive Status and Nutritional Markers in a Sample of Institutionalized Elderly People.Frontiers in aging neuroscience · 2022Article
- Strategies to evaluate outcomes in long-COVID-19 and post-COVID survivors.Infectious agents and cancer · 2021Article
- Association of 25-hydroxyvitamin D status with brain volume changes.Food science & nutrition · 2021Article
- The Association of Vitamin D and Neurodevelopmental Status Among 2 Years Old Infants.Global pediatric health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In recent years, emerging evidence has linked vitamin D not only to its known effects on calcium and bone metabolism, but also to many chronic illnesses involving neurocognitive decline. The importance of vitamin D3 in reducing the risk of these diseases continues to increase due to the fact that an increasing portion of the population in developed countries has a significant vitamin D deficiency. The older population is at an especially high risk for vitamin D deficiency due to the decreased cutaneous synthesis and dietary intake of vitamin D. Recent studies have confirmed an association between cognitive impairment, dementia, and vitamin D deficiency. There is a need for well-designed randomized trials to assess the benefits of vitamin D and lifestyle interventions in persons with mild cognitive impairment and dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.