Evidence map›Paper›PMID 24729676›Full record

ArticleTechnology (Elmsford, N.Y.)2013

An albumin leader sequence coupled with a cleavage site modification enhances the yield of recombinant C-terminal Mullerian Inhibiting Substance.

D Pépin, M Hoang, F Nicolaou, K Hendren, L A Benedict, A Al-Moujahed, A Sosulski, A Marmalidou, D Vavvas, P K Donahoe

Abstract read
In one paragraph

Article in Technology (Elmsford, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Clinical Utility of Anti-Mullerian Hormone in Pediatrics.The Journal of clinical endocrinology and metabolism · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Characterization of the molecular mechanisms that govern anti-Müllerian hormone synthesis and activity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Article
  8. A synopsis of global frontiers in fertility preservation.Journal of assisted reproduction and genetics · 2022
    Review
  9. A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Establishment of a WHO Reference Reagent for anti-Mullerian hormone.Reproductive biology and endocrinology : RB&E · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

D PépinPediatric Surgical Research Laboratories, Massachusetts General Hospital ; Harvard Medical School.
M HoangPediatric Surgical Research Laboratories, Massachusetts General Hospital ; Harvard Medical School ; Massachusetts Eye-Ear Infirmary.
F NicolaouPediatric Surgical Research Laboratories, Massachusetts General Hospital.
K HendrenPediatric Surgical Research Laboratories, Massachusetts General Hospital.
L A BenedictPediatric Surgical Research Laboratories, Massachusetts General Hospital ; Harvard Medical School.
A Al-MoujahedHarvard Medical School ; Massachusetts Eye-Ear Infirmary.
A SosulskiPediatric Surgical Research Laboratories, Massachusetts General Hospital ; Harvard Medical School.
A MarmalidouHarvard Medical School ; Massachusetts Eye-Ear Infirmary.
D VavvasHarvard Medical School ; Massachusetts Eye-Ear Infirmary.
P K DonahoePediatric Surgical Research Laboratories, Massachusetts General Hospital ; Harvard Medical School.
Harvard University · USMassachusetts General Hospital · USMassachusetts Eye and Ear Infirmary · US

Funding

MULLERIAN INHIBITING SUBSTANCER01CA017393 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DONAHOE, PATRICIA K · 1985 to 2009
$4.0M
NCI NIH HHS R01 CA017393
6 · The paper itself

Abstract

Mullerian Inhibiting Substance (MIS) has been shown to inhibit ovarian cancer cells both

Identifiers

PMID24729676
PMCPMC3980489
OpenAlexW2141051739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.