Evidence map›Paper›PMID 24729594›Full record

ArticleRadiation protection dosimetry2014

Advances in a framework to compare bio-dosimetry methods for triage in large-scale radiation events.

Ann Barry Flood, Holly K Boyle, Gaixin Du, Eugene Demidenko, Roberto J Nicolalde, Benjamin B Williams, Harold M Swartz

Abstract readComparative Study
In one paragraph

Article in Radiation protection dosimetry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Imaging tooth enamel using zero echo time (ZTE) magnetic resonance imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2015
    Article
  20. Proteomic Profiling for Serum Biomarkers in Mice Exposed to Ionizing Radiation.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ann Barry FloodGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA ann.b.flood@dartmouth.edu.
Holly K BoyleGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA.
Gaixin DuGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA.
Eugene DemidenkoGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA.
Roberto J NicolaldeNicolalde R&D, LLC, West Lebanon, NH, USA.
Benjamin B WilliamsGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA.
Harold M SwartzGeisel School of Medicine at Dartmouth, EPR Center, Hanover, NH 03768, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Scientific and Administrative Core: Dartmouth Medical SchoolU19AI091173 · NIAID · DARTMOUTH COLLEGE · PI SWARTS, STEVEN GREGORY · 2010 to 2014
$16.3M
NCI NIH HHS P30 CA023108NIAID NIH HHS U19AI091173PHS HHS HHSO100201100024C
6 · The paper itself

Abstract

Planning and preparation for a large-scale nuclear event would be advanced by assessing the applicability of potentially available bio-dosimetry methods. Using an updated comparative framework the performance of six bio-dosimetry methods was compared for five different population sizes (100-1,000,000) and two rates for initiating processing of the marker (15 or 15,000 people per hour) with four additional time windows. These updated factors are extrinsic to the bio-dosimetry methods themselves but have direct effects on each method's ability to begin processing individuals and the size of the population that can be accommodated. The results indicate that increased population size, along with severely compromised infrastructure, increases the time needed to triage, which decreases the usefulness of many time intensive dosimetry methods. This framework and model for evaluating bio-dosimetry provides important information for policy-makers and response planners to facilitate evaluation of each method and should advance coordination of these methods into effective triage plans.

Indexed as

Computer SimulationDisaster PlanningHumansModels, TheoreticalRadiation InjuriesRadiation MonitoringRadioactive Hazard ReleaseTriage

Identifiers

PMID24729594
PMCPMC4067227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.