Evidence map›Paper›PMID 2472936›Full record

ArticleChromosoma1989

A retroposon-like short repetitive DNA element in the genome of the human blood fluke, Schistosoma mansoni.

L D Spotila, H Hirai, D M Rekosh, P T Lo Verde

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Chromosoma, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Transposable Elements in the Genome of Human ParasiteTropical medicine and infectious disease · 2021
    Review
  3. Review
  4. Article
  5. Article
  6. Integration of reporter transgenes into Schistosoma mansoni chromosomes mediated by pseudotyped murine leukemia virus.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2008
    Article
  7. Article
  8. Article
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  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Real-time PCR for sexing Schistosoma mansoni cercariae.Molecular and biochemical parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L D SpotilaDepartment of Microbiology, State University of New York, Buffalo 14214.
H Hirai
D M Rekosh
P T Lo Verde
University at Buffalo, State University of New York · US

Funding

TOWARD A MOLECULARLY-DEFINED VACCINE FOR SCHISTOSOMIASISR01AI018867 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LOVERDE, PHILIP T · 1989 to 2009
$2.7M
THE GENETICS OF ADENOVIRUS DNA REPLICATIONK04CA000905 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI REKOSH, DAVID M · 1985 to 1989
–
TOWARD A MOLECULARLY-DEFINED VACCINE FOR SCHISTOSOMIASISR22AI018867 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LOVERDE, PHILIP T · 1985 to 1991
–
NCI NIH HHS CA-000905NIAID NIH HHS AI07161NIAID NIH HHS AI 18867
6 · The paper itself

Abstract

The genome of Schistosoma mansoni, a human blood fluke, contains a family of short repetitive DNA elements which we have named the SM alpha family. In this paper we report the sequences of two SM alpha family members which are derived from tandem arrangements and four family members which are dispersed copies. The two tandemly repeated copies are 331 and 335 bp, while the four dispersed copies range in size from 107 to 322 bp. Three dispersed copies are flanked by direct repeats and have AT-rich 3' ends. The tandem copies and one of the dispersed copies have regions of homology to RNA polymerase III promoters and arginine tRNA genes. In addition the repeated element is rearranged in two of the dispersed copies when compared with the other dispersed and two tandem copies. Localization studies show that SM alpha elements are distributed in the sex and autosomal chromosomes. These observations suggest that members of this family may have been dispersed throughout the genome via RNA intermediates.

Indexed as

Repetitive Sequences, Nucleic AcidAnimalsBase SequenceDNAFemaleGene RearrangementMaleMolecular Sequence DataMultigene FamilyNucleic Acid HybridizationRNASchistosoma mansoniSequence Homology, Nucleic AcidDNARNA

Identifiers

PMID2472936
OpenAlexW2044818693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.