Evidence map›Paper›PMID 24729222›Full record

ReviewAdvances in experimental medicine and biology2014

How in vivo EPR measures and images oxygen.

Boris Epel, Gage Redler, Howard J Halpern

Open access · greenAbstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Oxygen dynamics and delivery strategies to enhance beta cell replacement therapy.American journal of physiology. Cell physiology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Directional TV algorithm for fast EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024
    Article
  11. Article
  12. Article
  13. Amniotic growth factors enhanced human pre-adipocyte cell viability and differentiation under hypoxia.Journal of biomedical materials research. Part B, Applied biomaterials · 2022
    Article
  14. Small Animal IMRT Using 3D-Printed Compensators.International journal of radiation oncology, biology, physics · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Medical gas research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Boris EpelCenter for EPR Imaging In Vivo Physiology, Chicago, IL, USA.
Gage RedlerCenter for EPR Imaging In Vivo Physiology, Chicago, IL, USA.
Howard J HalpernCenter for EPR Imaging In Vivo Physiology, Chicago, IL, USA. h-halpern@uchicago.edu.
University of Chicago · US

Funding

Very Low Frequency EPR Imaging in Vivo Phisiology P41 EB02034P41EB002034 · NIBIB · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2017
$16.1M
Radiation Biology of EPR Oxygen ImagesR01CA098575 · NCI · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2022
$4.5M
NCI NIH HHS R01 CA098575NCI NIH HHS R01 CA98575NIBIB NIH HHS P41 EB002034
6 · The paper itself

Abstract

The partial pressure of oxygen (pO₂) in tissues plays an important role in the pathophysiology of many diseases and influences outcome of cancer therapy, ischemic heart and cerebrovascular disease treatments and wound healing. Over the years a suite of EPR techniques for reliable oxygen measurements has been developed. This is a mini-review of pulse EPR in vivo oxygen imaging methods that utilize soluble spin probes. Recent developments in pulse EPR imaging technology have brought an order of magnitude increase in image acquisition speed, enhancement of sensitivity and considerable improvement in the precision and accuracy of oxygen measurements.

Indexed as

Electron Spin Resonance SpectroscopyOxygenReproducibility of ResultsOxygen

Identifiers

PMID24729222
PMCPMC4319367
OpenAlexW132698564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.