ReviewDevelopmental psychobiology2015
Developmental and contextual considerations for adrenal and gonadal hormone functioning during adolescence: Implications for adolescent mental health.
Review in Developmental psychobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- The Dynamic Interplay Between Puberty and Structural Brain Development as a Predictor of Mental Health Difficulties in Adolescence: A Systematic Review.Biological psychiatry · 2024Pooled it
- A systematic review of adrenarche as a sensitive period in neurobiological development and mental health.Developmental cognitive neuroscience · 2017Pooled it
- The association between pubertal timing and diurnal cortisol activity in middle adolescence.Stress (Amsterdam, Netherlands) · 2026Article
- The sex-specific role of adrenal androgens in youth psychopathology.Translational psychiatry · 2026Article
- Links between hormonal and pubertal development, and adolescent females' risk for affective symptoms.Psychoneuroendocrinology · 2026Article
- Adrenal Biomarkers of Stress in Transgender and Gender-Diverse Adolescents.Developmental psychobiology · 2026Article
- Mixed evidence for stress effects on cortisol-testosterone coupling in Syrian refugee and Jordanian non-refugee adolescents.Psychoneuroendocrinology · 2026Article
- Age-Dependent Effects of Heavy Metals on the Hypothalamic-Pituitary-Testicular Axis-Related Hormones in Men.Toxics · 2026Article
- Does including multiple hormones and family context together clarify hormone-behavior associations? A systematic review.Comprehensive psychoneuroendocrinology · 2025Review
- Article
- Positive Cortisol-Testosterone Hormonal Coupling Among Adolescents in Argentina and Jordan.American journal of biological anthropology · 2025Article
- Sex differences in associations between hair glucocorticoids and internalizing symptoms in adolescents.Comprehensive psychoneuroendocrinology · 2025Article
- Impact of adolescent high-fat diet and psychosocial stress on neuroendocrine stress responses and binge eating behavior in adult male Lewis rats.Hormones and behavior · 2025Article
- Hair cortisol concentrations are associated with greater adiposity in late adolescence amongst non-Hispanic White individuals.Pediatric obesity · 2024Article
- Longitudinal analysis of cortisol changes during pubertal development in indigenous Qom girls.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Within-person biological mechanisms of mood variability in childhood and adolescence.Human brain mapping · 2024Article
- The cortisol/DHEA ratio mediates the association between early life stress and externalizing problems in adolescent boys.Psychoneuroendocrinology · 2024Article
- Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences.Frontiers in neuroendocrinology · 2024Review
- Depressive and anxiety disorders and antidepressant prescriptions among insured children and young adults with congenital adrenal hyperplasia in the United States.Frontiers in endocrinology · 2023Article
- Transgenerational effect of Mothers' experiences of discrimination on Black youths' hormone coupling in response to laboratory stress.Research in human development · 2023Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Substantial research has implicated the hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-gonadal (HPG) axes independently in adolescent mental health problems, though this literature remains largely inconclusive. Given the cross-talk between the HPA and HPG axes and their increased activation in adolescence, a dual-axis approach that examines both axes simultaneously is proposed to predict the emergence and persistence of adolescent mental health problems. After briefly orienting readers to HPA and HPG axis functioning, we review the literature examining associations between hormone levels and changes with behavior during adolescence. Then, we provide a review of the literature supporting examination of both axes simultaneously and present the limited research that has taken a dual-axis approach. We propose future directions including consideration of between-person and within-person approaches to address questions of correlated changes in HPA and HPG hormones. Potential moderators are considered to increase understanding of the nuanced hormone-behavior associations during key developmental transitions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.