ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Longitudinal changes in health-related quality of life in normal glucose tolerance, prediabetes and type 2 diabetes: results from the KORA S4/F4 cohort study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Quality of life and mental health measurements among patients with type 2 diabetes mellitus: a systematic review.Health and quality of life outcomes · 2023Pooled it
- Similarities and Differences of Mental Health in Women and Men: A Systematic Review of Findings in Three Large German Cohorts.Frontiers in public health · 2021Pooled it
- The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study.PloS one · 2019Trial
- Long-Term Effectiveness of a Stress Management Intervention at Work: A 9-Year Follow-Up Study Based on a Randomized Wait-List Controlled Trial in Male Managers.BioMed research international · 2017Trial
- Assessing the Impact of Hypertension on Health-Related Quality of Life: Insights from Sociodemographic, Economic, and Clinical Features Using SF-36.Healthcare (Basel, Switzerland) · 2025Article
- Glycemic status and health-related quality of life (HRQOL) in populations at risk of diabetes in two Latin American cities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Health-related quality of life (HRQoL) in a population at risk of type 2 diabetes: a cross-sectional study in two Latin American cities.Health and quality of life outcomes · 2021Article
- The association between the risk of developing type 2 diabetes mellitus and health-related quality of life: baseline results from the Dimini lifestyle intervention.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- The influencing factors of health-related quality of life among rural hypertensive individuals: a cross-sectional study.Health and quality of life outcomes · 2021Article
- Diabetes and impaired fasting glucose in a population-based sample of individuals aged 75 + years: associations with cognition, major depressive disorder, functionality and quality of life-the Pietà study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Impaired glucose regulation, depressive symptoms, and health-related quality of life.BMJ open diabetes research & care · 2020Article
- Article
- Comparison of health-related quality of Life (HRQOL) among patients with pre-diabetes, diabetes and normal glucose tolerance, using the 15D-HRQOL questionnaire in Greece: the DEPLAN study.BMC endocrine disorders · 2018Article
- Article
- Determinants of Change in Glycemic Status in Individuals with Prediabetes: Results from a Nationwide Cohort Study in Germany.Journal of diabetes research · 2018Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to examine how transition between normal glucose tolerance, prediabetes and diabetes over a 7 year period is associated with change in health-related quality of life (HRQL) in an elder German population-based cohort.
methodsWe used data from 1,046 participants of the KORA S4/F4 cohort study aged 55-74 years at baseline. Based on an oral glucose tolerance test, prediabetes was defined as impaired fasting glucose and/or impaired glucose tolerance. HRQL was assessed with the SF-12 questionnaire. Using linear regression, we estimated mean change in HRQL over time, depending on glucose status at baseline and follow-up, adjusted by demographic and lifestyle variables.
resultsIndividuals progressing to prediabetes or diabetes experienced a greater loss in the physical component score than patients with persistent normal glucose tolerance (-2.31 and -7.44 vs. -1.08), but the difference was only significant for subjects converting to diabetes. Subjects with prediabetes at baseline and diabetes at follow-up had a significant loss in mental health compared to subjects with persistent prediabetes.
conclusionsThere is first evidence that worsening of glucose metabolism over time is associated with deteriorating HRQL, however, further and larger longitudinal studies are needed to confirm these findings.
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