ArticleDigestive diseases and sciences2014
Characteristics and management of patients with chronic hepatitis B in an integrated care setting.
Article in Digestive diseases and sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Estimating the proportion of people with chronic hepatitis B virus infection eligible for hepatitis B antiviral treatment worldwide: a systematic review and meta-analysis.The lancet. Gastroenterology & hepatology · 2021Pooled it
- Current Tools to Diagnose and Predict Hepatocellular Carcinoma: Relevance to HIV and Hepatitis B Virus Coinfection.Current HIV/AIDS reports · 2025Review
- Chronic viral hepatitis B: evaluation of the care of patients monitored at the SMIT in Tivaouane, Sénégal.IJID regions · 2025Article
- Expanding treatment indications in chronic hepatitis B: Should we treat all patients?Hepatology international · 2025Review
- It Is Time for a Simplified Approach to Hepatitis B Elimination.Gastro hep advances · 2023Article
- Gaps in hepatocellular carcinoma surveillance among insured patients with hepatitis B infection without cirrhosis in the United States.Hepatology communications · 2022Article
- A Comprehensive Nursing Model Combined with High-Quality Nursing Intervention for Antiviral Therapy in Patients with Chronic Hepatitis B.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Epidemiology and Prevention of Tuberculosis and Chronic Hepatitis B Virus Infection in the United States.Journal of immigrant and minority health · 2021Review
- Does Provider Type Affect Bone Health Surveillance in Chronic Pancreatitis?Digestive diseases and sciences · 2021Article
- Hepatitis B Evaluation and Linkage to Care for Newly Arrived Refugees: A Multisite Quality Improvement Initiative.Journal of immigrant and minority health · 2021Article
- Drug Treatment of Patients with Liver Cirrhosis in a Tertiary Hospital in Northern Ghana: Does It Comply with Recommended Guidelines?International journal of hepatology · 2020Article
- Barriers to Disease Monitoring and Liver Cancer Surveillance Among Patients with Chronic Hepatitis B in the United States.Journal of community health · 2019Review
- A Comparison Between Community and Academic Practices in the USA in the Management of Chronic Hepatitis B Patients Receiving Entecavir: Results of the ENUMERATE Study.Digestive diseases and sciences · 2019Article
- Status of, and strategies for improving, adherence to HCC screening and surveillance.Journal of hepatocellular carcinoma · 2019Review
- Disparities in mortality for chronic liver disease among Asian subpopulations in the United States from 2007 to 2016.Journal of viral hepatitis · 2018Article
- Provider, Patient, and Practice Factors Shape Hepatitis B Prevention and Management by Primary Care Providers.Journal of clinical gastroenterology · 2017Article
- Article
- Improving Healthcare Systems to Reduce Healthcare Disparities in Viral Hepatitis.Digestive diseases and sciences · 2016Review
- The role of the general practitioner in the screening and clinical management of chronic viral hepatitis in six EU countries.Journal of preventive medicine and hygiene · 2016Review
- Hepatitis B among Asian Americans: Prevalence, progress, and prospects for control.World journal of gastroenterology · 2015Review
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Authors and funding
7 authors.
Funding
Abstract
backgroundFew population-based studies have described characteristics and management of patients with chronic hepatitis B (CHB) in the USA.
methodsWe retrospectively studied adults with CHB in the Northern California Kaiser Permanente Medical Care Program (KPNC) from July 2009 to December 2010 (n = 12,016). Laboratory tests, treatment patterns, and hepatocellular carcinoma (HCC) surveillance were ascertained during a "recent" 18-month study window (July 2009-December 2010), or as "ever" based on records dating to 1995.
resultsThe mean age was 49 years; 51 % were men, 83 % Asian, and 87 % KPNC members >5 years. Overall, 51 % had ≥ 1 liver-related visit, 14 % with gastroenterology or infectious disease specialists, and 37 % with primary care providers (PCP) only. Less than 40 % of patients had both hepatitis B virus (HBV) DNA and ALT testing conducted recently, while 56 % of eligible patients had received HCC surveillance. Recent laboratory testing and HCC surveillance were more frequent in patients seen by a specialist versus PCP only (90 vs. 47 % and 92 vs. 73 %, respectively, p values <0.001). During the study period, 1,649 (14 %) received HBV treatment, while 5 % of untreated patients had evidence of treatment eligibility. Among 599 patients newly initiated on HBV therapy, 76 % had guideline-based indications for treatment.
conclusionsMost patients initiated on HBV treatment met eligibility, and very few patients with evidence of needing treatment were left untreated. However, monitoring of ALT and HBV DNA levels, as well as HCC surveillance, were not frequent, underestimating the proportion of patients that warranted HBV therapy. Viral monitoring and cancer surveillance are therefore important targets for improving the scope of CHB care in the community setting.
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