Evidence map›Paper›PMID 24728785›Full record

GuidelineJournal of neuro-oncology2014

The role of radiotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.

Samuel Ryu, John M Buatti, Ann Morris, Steven N Kalkanis, Timothy Charles Ryken, Jeffrey J Olson, AANS/CNS Joint Guidelines Committee

Abstract readPractice GuidelineSystematic Review
PubMed Publisher
In one paragraph

Guideline in Journal of neuro-oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prospective randomized clinical studies involving reirradiation : Lessons learned.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2016
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Updates in IDH-Wildtype Glioblastoma.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Review
  7. Review
  8. Review
  9. Reoperation for recurrent glioblastomas: What to expect?Surgical neurology international · 2021
    Article
  10. Article
  11. Re-irradiation for recurrent glioblastoma multiforme: a critical comparison of different concepts.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Treatment of glioblastoma in adults.Therapeutic advances in neurological disorders · 2018
    Review
  17. Article
  18. Article
  19. Expert consensus on re-irradiation for recurrent glioma.Radiation oncology (London, England) · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samuel RyuDepartment of Radiation Oncology, Stony Brook University School of Medicine, Stony Brook, NY, USA, samuel.ryu@stonybrookmedicine.edu.
John M Buatti
Ann Morris
Steven N Kalkanis
Timothy Charles Ryken
Jeffrey J Olson
AANS/CNS Joint Guidelines Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

questionCan re-irradiation (by using conventional radiotherapy, fractionated radiosurgery, or single fraction radiosurgery) be used in patients with progressive glioblastoma multiforme after the first adjuvant combined multimodality treatment with radiation and chemotherapy? TARGET POPULATION: These recommendations apply to adult patients with progressive glioblastoma after first line combined multimodality treatment with chemotherapy and radiation. RECOMMENDATIONS LEVEL III: When the target tumor is amenable for additional radiation, re-irradiation is recommended as it provides improved local tumor control, as measured by best imaging response. Such re-irradiation can take the form of conventional fractionation radiotherapy, fractionated radiosurgery, or single fraction radiosurgery. LEVEL III: Re-irradiation is recommended in order to maintain or improve a patient's neurological status and quality of life prior to any further tumor progression.

Indexed as

AdultBrain NeoplasmsCranial IrradiationEvidence-Based MedicineGlioblastomaHumansNeoplasm Recurrence, LocalRadiosurgeryTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.