Observational studyHernia : the journal of hernias and abdominal wall surgery2015
Complex ventral hernia repair with a human acellular dermal matrix.
Observational study in Hernia : the journal of hernias and abdominal wall surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Biologic Mesh in Surgery: A Comprehensive Review and Meta-Analysis of Selected Outcomes in 51 Studies and 6079 Patients.World journal of surgery · 2021Pooled it
- Combined use of composite mesh and acellular dermal matrix graft for abdominal wall repair following tumour resection.World journal of surgical oncology · 2024Article
- Abdominal wall hernia repair: from prosthetic meshes to smart materials.Materials today. Bio · 2023Review
- Transcriptomic Regulation of Macrophages by Matrix-Bound Nanovesicle-Associated Interleukin-33.Tissue engineering. Part A · 2022Article
- Comparison of component separation technique, partition technique, and extended anterolateral thigh flap in complex abdominal wall closure.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Regenerative Engineering: Current Applications and Future Perspectives.Frontiers in surgery · 2021Review
- Early outcomes of an enhanced recovery protocol for open repair of ventral hernia.Surgical endoscopy · 2018Article
- Scarring vs. functional healing: Matrix-based strategies to regulate tissue repair.Advanced drug delivery reviews · 2018Review
- Predictors of outpatient resource utilization following ventral and incisional hernia repair.Surgical endoscopy · 2018Article
- Ventral hernia repair with poly-4-hydroxybutyrate mesh.Surgical endoscopy · 2018Article
- Paraesophageal Hiatal Hernia Repair With Urinary Bladder Matrix Graft.JSLS : Journal of the Society of Laparoendoscopic SurgeonsObservational
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe ideal approach to complex ventral hernia repair is frequently debated. Differences in processing techniques among biologic materials may impact hernia repair outcomes. This study evaluates the outcomes of hernia repair with a terminally sterilized human acellular dermal matrix (TS-HADM) (AlloMax(®) Surgical Graft, by C. R. Bard/Davol, Inc., Warwick, RI, USA) treated with low-dose gamma irradiation.
methodsA single-arm multi-center retrospective observational study of patients undergoing hernia repair with TS-HADM was performed. Data analyses were exploratory only; no formal hypothesis testing was pre-specified.
resultsSeventy-eight patients (43F, 35M) underwent incisional hernia repair with a TS-HADM. Mean follow-up was 20.5 months. Preoperative characteristics include age of 56.6 ± 11.1 years, BMI 36.7 ± 9.9 kg/m(2), and mean hernia defect size 187 cm(2). Sixty-five patients underwent component separation technique (CST) with a reinforcing graft. Overall, 21.8% developed recurrences. Recurrences occurred in 15% of patients repaired with CST. Major wound complications occurred in 31% of patients overall. Based upon CDC surgical wound classification, major wound complications were seen in 26, 40, 56, and 50% of Class 1, 2, 3, and 4 wounds, respectively. No grafts required removal.
conclusionsHernia recurrences are not uncommon following complex abdominal wall reconstruction. Improved outcomes are seen when a TS-HADM is utilized as reinforcement to primary fascial closure.
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