Evidence map›Paper›PMID 24728479›Full record

ArticleScientific reports2014

Whole-genome sequencing of Berkshire (European native pig) provides insights into its origin and domestication.

Mingzhou Li, Shilin Tian, Carol K L Yeung, Xuehong Meng, Qianzi Tang, Lili Niu, Xun Wang, Long Jin, Jideng Ma, Keren Long and 9 more

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  14. The History of Lentil (Frontiers in plant science · 2021
    Article
  15. Genomic Variation Landscape of the Model Salt CressFrontiers in plant science · 2021
    Article
  16. Genomic and Phenotypic Divergence in Wild Barley Driven by Microgeographic Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mingzhou Li1] Biodynamic Optical Imaging Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, and School of Life Sciences, Peking University, Beijing 100871, People's Republic of China [2] Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China [3].
Shilin Tian1] Novogene Bioinformatics Institute, Beijing 100083, People's Republic of China [2].
Carol K L Yeung1] Novogene Bioinformatics Institute, Beijing 100083, People's Republic of China [2].
Xuehong MengNovogene Bioinformatics Institute, Beijing 100083, People's Republic of China.
Qianzi TangInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Lili NiuInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Xun WangInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Long JinInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Jideng MaInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Keren LongInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Chaowei Zhou1] Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China [2] Department of Animal Science, Southwest University at Rongchang, Chongqing 402460, People's Republic of China.
Yinchuan CaoNovogene Bioinformatics Institute, Beijing 100083, People's Republic of China.
Li ZhuInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Lin BaiInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Guoqing TangInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Yiren GuSichuan Animal Science Academy, Chengdu 610066, People's Republic of China.
An'an JiangInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Xuewei LiInstitute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, People's Republic of China.
Ruiqiang Li1] Biodynamic Optical Imaging Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, and School of Life Sciences, Peking University, Beijing 100871, People's Republic of China [2] Novogene Bioinformatics Institute, Beijing 100083, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domesticated organisms have experienced strong selective pressures directed at genes or genomic regions controlling traits of biological, agricultural or medical importance. The genome of native and domesticated pigs provide a unique opportunity for tracing the history of domestication and identifying signatures of artificial selection. Here we used whole-genome sequencing to explore the genetic relationships among the European native pig Berkshire and breeds that are distributed worldwide, and to identify genomic footprints left by selection during the domestication of Berkshire. Numerous nonsynonymous SNPs-containing genes fall into olfactory-related categories, which are part of a rapidly evolving superfamily in the mammalian genome. Phylogenetic analyses revealed a deep phylogenetic split between European and Asian pigs rather than between domestic and wild pigs. Admixture analysis exhibited higher portion of Chinese genetic material for the Berkshire pigs, which is consistent with the historical record regarding its origin. Selective sweep analyses revealed strong signatures of selection affecting genomic regions that harbor genes underlying economic traits such as disease resistance, pork yield, fertility, tameness and body length. These discoveries confirmed the history of origin of Berkshire pig by genome-wide analysis and illustrate how domestication has shaped the patterns of genetic variation.

Indexed as

GenomeAnimalsAnimals, DomesticBody SizeChromosome MappingHigh-Throughput Nucleotide SequencingINDEL MutationPhylogenyPolymorphism, Single NucleotideSelection, GeneticSequence Analysis, DNASwine

Identifiers

PMID24728479
PMCPMC3985078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.