ArticleEinstein (Sao Paulo, Brazil)
Analysis of oxybutynin treatment for hyperhidrosis in patients aged over 40 years.
Article in Einstein (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03694093 (A Prospective Study Assessing the Effect of Patient Characteristics on Treatment Response in Hyperhidrosis), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Study Assessing the Effect of Patient Characteristics on Treatment Response in Hyperhidrosis
Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Colchicine for preventing stroke in patients with and without intracranial atherosclerotic stenosis: a prespecified analysis of a randomized clinical trial.EClinicalMedicine · 2025Article
- Oxybutynin for the Treatment of Primary Hyperhidrosis: Current State of the Art.Skin appendage disorders · 2015Review
- Management of hyperhidrosis.Clinical, cosmetic and investigational dermatology · 2014Review
- Oxybutynin as an alternative treatment for hyperhidrosis.Anais brasileiros de dermatologiaReview
- Epidemiologic analysis of prevalence of the hyperhidrosis.Anais brasileiros de dermatologiaArticle
- Efficacy, Safety and Quality of Life of Oxybutynin versus Aluminum Chloride Hexahydrate in Treating Primary Palmar Hyperhidrosis.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOur aim was to analyze the effectiveness of oxybutynin for hyperhidrosis treatment in patients over 40 years.
methodsEighty-seven patients aged over 40 years were divided into two groups. One group consisted of 48 (55.2%) patients aged between 40 and 49 years, and another was composed of 39 (44.8%) patients aged over 50 years (50 to 74 years). A comparative analysis of Quality of Life and level of hyperhidrosis between the groups was carried out 6 weeks after a protocol treatment with oxybutynin. A validated clinical questionnaire was used for evaluation.
resultsIn the younger age group, 75% of patients referred a "partial" or "great" improvement in level of hyperhidrosis after treatment. This number was particularly impressive in patients over 50 years, in which 87.2% of the cases demonstrated similar levels of improvement. Over 77% of patients in both groups demonstrated improvement in Quality of Life. Excellent outcomes were observed in older patients, in which 87.1% of patients presented "slightly better" (41%) or "much better" (46.1%) improvement.
conclusionPatients aged over 40 years with hyperhidrosis presented excellent results after oxybutynin treatment. These outcomes were particularly impressive in the age group over 50 years, in which most patients had significant improvement in Quality of Life and in level of hyperhidrosis.
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Registered trials
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