SynthesisAnnals of internal medicine2014
Functional status and quality of life after transcatheter aortic valve replacement: a systematic review.
Synthesis in Annals of internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Preoperative Anemia and Postoperative Mortality in Patients with Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation (TAVI): A Systematic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019Pooled it
- Transcatheter vs surgical aortic-valve replacement in low- to intermediate-surgical-risk candidates: A meta-analysis and systematic review.Clinical cardiology · 2017Pooled it
- The relationship between preoperative frailty and outcomes following transcatheter aortic valve implantation: a systematic review and meta-analysis.European heart journal. Quality of care & clinical outcomes · 2017Pooled it
- Temporal Trends in Quality of Life Outcomes After Transapical Transcatheter Aortic Valve Replacement: A Placement of AoRTic TraNscathetER Valve (PARTNER) Trial Substudy.Circulation. Cardiovascular quality and outcomes · 2015Trial
- Differential impact of institutional procedural volume on outcomes of transcatheter and surgical strategies for concomitant aortic stenosis and coronary artery disease: a nationwide registry study.Cardiovascular intervention and therapeutics · 2026Article
- Article
- Early Post-TAVI Physical Activity After Eccentric Training Compared to Standard Practice - Results of a Feasibility Study.Clinical interventions in aging · 2026Article
- From symptoms to strategy: pre-procedural NYHA-class as a key to risk stratification and personalized TAVR-management.Frontiers in cardiovascular medicine · 2026Article
- Stress Echocardiography in Aortic Stenosis: From Diagnostic Challenges to Guideline-Endorsed Clinical Applications.Journal of clinical medicine · 2025Article
- Permanent pacemaker dependency after transcatheter aortic valve implantation: Prevalence, patients' characteristics, and main determinants.Heart rhythm O2 · 2025Article
- The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement.Scientific reports · 2025Article
- Aortic valve replacement in uncontrolled diabetes: a matter of causes - effect.International journal of cardiology. Heart & vasculature · 2025Article
- Long-Term Outcome of Elderly Patients with Severe Aortic Stenosis Undergoing a Tailored Interventional Treatment Using Frailty-Based Management: Beyond the Five-Year Horizon.Journal of personalized medicine · 2024Article
- Added Value of Medical Subject Headings Terms in Search Strategies of Systematic Reviews: Comparative Study.Journal of medical Internet research · 2024Article
- Evaluating the Sensitivity of Wearable Devices in Posttranscatheter Aortic Valve Implantation Functional Assessment.JMIR mHealth and uHealth · 2024Article
- Pre-procedural nursing home length of stay and outcomes of transcatheter aortic valve replacement.Journal of the American Geriatrics Society · 2024Article
- Article
- Quality of life and functional capacity in patients after cardiac surgery intensive care unit.World journal of cardiology · 2024Review
- Cardiac Health Assessment Using a Wearable Device Before and After Transcatheter Aortic Valve Implantation: Prospective Study.JMIR mHealth and uHealth · 2024Article
- Exercise-based real-time telerehabilitation for older patients recently discharged after transcatheter aortic valve implantation: An extended feasibility study.Journal of geriatric cardiology : JGC · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe functional and quality-of-life benefits of transcatheter aortic valve replacement (TAVR) have not been established. PURPOSE: To evaluate the changes in functional status and quality of life after TAVR. DATA SOURCES: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials from 1 January 2002 to 30 September 2013. STUDY SELECTION: Studies of TAVR that reported the New York Heart Association (NYHA) class, Short Form-12/36 Health Survey physical and mental component summary (points), or other measures of functional status. DATA EXTRACTION: Two reviewers independently extracted the mean change (follow-up minus baseline) in primary outcomes. Because of substantial heterogeneity, data were not pooled; the range of mean change was summarized. DATA SYNTHESIS: We identified 60 observational studies (56 pre–post comparison and 4 head-to-head comparative studies) and 2 randomized, controlled trials (11 205 patients). Most studies showed a clinically important decrease in NYHA class at 6 to 11 months (range, -0.8 to -2.1 classes) and 12 to 23 months (range, -0.8 to -2.1 classes). The improvement in the Short Form-12/36 Health Survey physical component score was clinically important over 12 months (range, 4.9 to 26.9 points), and the change in mental component score was smaller (range, 1.0 to 8.9 points).Clinically important improvements were seen in other disease-specific measures but were less consistently seen in general health measures. LIMITATIONS: Comparative evidence is limited by few head-to-head studies. Survivor bias may have overestimated the benefits.
conclusionTranscatheter aortic valve replacement provides clinically important benefits in physical function and disease-specific measures of quality of life but modest benefits in psychological and general health measures. More comparative studies on functional status and quality of life are needed for informed treatment decision making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.