ArticleNature methods2014
Rapid adaptive optical recovery of optimal resolution over large volumes.
Article in Nature methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
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Who cites it
121 citing papers in PubMed.
- Graph-based modeling of optical system enables adaptive optics on dynamic samples with self-calibration.iScience · 2026Article
- Fast volumetric imaging of a zebrafish seizure model with adaptive optics light sheet microscopy.Biomedical optics express · 2026Article
- A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms.Nature methods · 2026Article
- Physics-informed multi-encoder adaptive optics enables rapid aberration correction for intravital microscopy of deep complex tissue.Nature communications · 2026Article
- Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields.Nature methods · 2026Article
- High-fidelity intravital imaging of biological dynamics with latent-space-enhanced digital adaptive optics.Nature biotechnology · 2026Article
- Review
- Enhancing volumetric microscopy with blind computational correction of spatially variant aberrations using neural field representation.bioRxiv : the preprint server for biology · 2026Article
- Machine learning assisted wavefront sensor.Proceedings of SPIE--the International Society for Optical Engineering · 2026Article
- Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice.Nature communications · 2025Article
- Fourier-based three-dimensional multistage transformer for aberration correction in multicellular specimens.Nature methods · 2025Article
- Compressive Fourier-Domain Intensity Coupling (C-FOCUS) enables near-millimeter deep imaging in the intact mouse brain in vivo.Research square · 2025Article
- Multiphoton Neurophotonics: Recent Advances in Imaging and Manipulating Neuronal Circuits.ACS photonics · 2025Review
- A Multimodal Adaptive Optical Microscope ForbioRxiv : the preprint server for biology · 2025Article
- Fourier-Based 3D Multistage Transformer for Aberration Correction in Multicellular Specimens.ArXiv · 2025Article
- Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy.Nature communications · 2025Article
- Image processing tools for petabyte-scale light sheet microscopy data.Nature methods · 2024Article
- Experimental characterization of an isoplanatic patch in mouse cortex using adaptive optics.Biomedical optics express · 2024Article
- Applications of Lightsheet Fluorescence Microscopy by High Numerical Aperture Detection Lens.The journal of physical chemistry. B · 2024Review
- Review
61 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors.
Funding
Abstract
Using a descanned, laser-induced guide star and direct wavefront sensing, we demonstrate adaptive correction of complex optical aberrations at high numerical aperture (NA) and a 14-ms update rate. This correction permits us to compensate for the rapid spatial variation in aberration often encountered in biological specimens and to recover diffraction-limited imaging over large volumes (>240 mm per side). We applied this to image fine neuronal processes and subcellular dynamics within the zebrafish brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.