Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2014
Exploring the "active ingredients" of an online smoking intervention: a randomized factorial trial.
Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00992264 (Optimizing an Online Motivational Tobacco Cessation Program), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing an Online Motivational Tobacco Cessation Program
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Internet-based interventions for smoking cessation.The Cochrane database of systematic reviews · 2017Pooled it
- Technology-delivered adaptations of motivational interviewing for health-related behaviors: A systematic review of the current research.Patient education and counseling · 2016Pooled it
- Feasibility, Acceptability, and Potential Impact of a Novel mHealth App for Smokers Ambivalent About Quitting: Randomized Pilot Study.JMIR mHealth and uHealth · 2023Trial
- Measuring Acceptability and Engagement of The Keep It Up! Internet-Based HIV Prevention Randomized Controlled Trial for Young Men Who Have Sex With Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2019Trial
- A Randomized Controlled Trial of an Optimized Smoking Treatment Delivered in Primary Care.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018Trial
- Improving Adherence to Smoking Cessation Treatment: Smoking Outcomes in a Web-based Randomized Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018Trial
- Customized recommendations and reminder text messages for automated, computer-based treatment during methadone.Experimental and clinical psychopharmacology · 2017Trial
- Linking smokers to a quitline: randomized controlled effectiveness trial of a support person intervention that targets non-smokers.Health education research · 2017Trial
- Treatment seeking as a mechanism of change in a randomized controlled trial of a mobile health intervention to support recovery from alcohol use disorders.Journal of substance abuse treatment · 2017Trial
- Improving Adherence to Smoking Cessation Treatment: Intervention Effects in a Web-Based Randomized Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017Trial
- Article
- A Novel mHealth App for Smokers Living With HIV Who Are Ambivalent About Quitting Smoking: Formative Research and Randomized Feasibility Study.JMIR formative research · 2024Article
- One view of the next decade of research on behavioral and biobehavioral approaches to cancer prevention and control: intervention optimization.Translational behavioral medicine · 2021Review
- Barriers to Building More Effective Treatments: Negative Interactions Amongst Smoking Intervention Components.Clinical psychological science : a journal of the Association for Psychological Science · 2021Article
- The association between frequency of e-cigarette use and long-term smoking cessation outcomes among treatment-seeking smokers receiving a behavioral intervention.Drug and alcohol dependence · 2021Article
- How to optimise public health interventions: a scoping review of guidance from optimisation process frameworks.BMC public health · 2020Article
- Development of a Mobile Health Intervention with Personal Experiments for Smokers Who Are Ambivalent About Quitting: Formative Design and Testing.JMIR formative research · 2020Article
- Optimizing Text Messages to Promote Engagement With Internet Smoking Cessation Treatment: Results From a Factorial Screening Experiment.Journal of medical Internet research · 2020Article
- Collecting outcome data of a text messaging smoking cessation intervention with in-program text assessments: How reliable are the results?Addictive behaviors · 2018Article
- Implementing Clinical Research Using Factorial Designs: A Primer.Behavior therapy · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
introductionResearch needs to systematically identify which components increase online intervention effectiveness (i.e., active ingredients). This study explores the effects of 4 potentially important design features in an Internet-based, population-level smoking intervention.
methodsSmokers (n = 1,865) were recruited from a large health care organization, regardless of readiness to quit. Using a full factorial design, participants were randomized to 1 of the 2 levels of each experimental factor (message tone [prescriptive vs. motivational], navigation autonomy [dictated vs. not], e-mail reminders [yes vs. no], and receipt of personally tailored testimonials [yes vs. no]) and provided access to the online intervention. Primary outcomes were self-reported 7-day point-prevalent smoking abstinence and confirmed utilization of adjunct treatment (pharmacotherapy or phone counseling) available through the health plan at 1 year. Outcomes were also assessed at 2 and 6 months and were examined among all enrolled participants (intent-to-treat [ITT]) and all who viewed the intervention (modified ITT).
resultsAt 1 year, 13.7% were abstinent and 26.0% utilized adjunct treatment. None of the contrasting factor levels differentially influenced abstinence or treatment utilization at 12 months. In the modified ITT sample, smokers receiving testimonials were less likely to use adjunct treatment at 6 months (odds ratio = 0.54, 95% confidence interval = 0.30-0.98, p = .04).
conclusionsNone of the design features enhanced treatment outcome. The negative effect observed for testimonials is provocative, but it should be viewed with caution. This study offers a model for future research testing the "active ingredients" of online interventions.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.