ReviewSeminars in cell & developmental biology2014
Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis.
Review in Seminars in cell & developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Review
- Microtubule Cytoskeleton and Spermatogenesis-Lesson From Studies of Toxicant Models.Toxicological sciences : an official journal of the Society of Toxicology · 2020Review
- Toxicological Effects of Cadmium on Mammalian Testis.Frontiers in genetics · 2020Review
- Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer.Molecular & cellular proteomics : MCP · 2019Article
- Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells.Scientific reports · 2016Article
- Regulation of blood-testis barrier by actin binding proteins and protein kinases.Reproduction (Cambridge, England) · 2016Review
- Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells.Basic and clinical andrology · 2016Article
- Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015Article
- Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice.Scientific reports · 2015Article
- Sertoli cells are the target of environmental toxicants in the testis - a mechanistic and therapeutic insight.Expert opinion on therapeutic targets · 2015Review
- Actin binding proteins, spermatid transport and spermiation.Seminars in cell & developmental biology · 2014Review
- Ezrin: a regulator of actin microfilaments in cell junctions of the rat testis.Asian journal of andrologyReview
- Kinases as targets for chemical modulators: Structural aspects and their role in spermatogenesis.SpermatogenesisReview
- Toxicants target cell junctions in the testis: Insights from the indazole-carboxylic acid model.SpermatogenesisReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Non-receptor protein tyrosine kinases are cytoplasmic kinases that activate proteins by phosphorylating tyrosine residues, which in turn affect multiple functions in eukaryotic cells. Herein, we focus on the role of non-receptor protein tyrosine kinases, most notably, FAK, c-Yes and c-Src, in the transport of spermatids across the seminiferous epithelium during spermatogenesis. Since spermatids, which are formed from spermatocytes via meiosis, are immotile haploid cells, they must be transported by Sertoli cells across the seminiferous epithelium during the epithelial cycle of spermatogenesis. Without the timely transport of spermatids across the epithelium, the release of sperms at spermiation fails to occur, leading to infertility. Thus, the molecular event pertinent to spermatid transport is crucial to spermatogenesis. We provide a critical discussion based on recent findings in this review. We also provide a hypothetical model on spermatid transport, and the role of non-receptor protein tyrosine kinases in this event. We also highlight areas of research that deserve attention by investigators in the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.