ArticleG3 (Bethesda, Md.)2014
Rapid evolution of phenotypic plasticity and shifting thresholds of genetic assimilation in the nematode Caenorhabditis remanei.
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Limited plasticity in thermally tolerant ectotherm populations: evidence for a trade-off.Proceedings. Biological sciences · 2021Pooled it
- Experimental Evolution in a Warming World: The Omics Era.Molecular biology and evolution · 2024Review
- Threshold shifts and developmental temperature impact trade-offs between tolerance and plasticity.Proceedings. Biological sciences · 2024Article
- Comparative Transcriptome Analyses Provide New Insights into the Evolution of Divergent Thermal Resistance in Two Eel Gobies.Current issues in molecular biology · 2023Article
- Pathogenicity of the root lesion nematode Pratylenchus neglectus depends on pre-culture conditions.Scientific reports · 2023Article
- Genomic diversity landscapes in outcrossing and selfing Caenorhabditis nematodes.PLoS genetics · 2023Article
- Loss of transcriptional plasticity but sustained adaptive capacity after adaptation to global change conditions in a marine copepod.Nature communications · 2022Article
- Inheritance of Acquired Traits in Insects and Other Animals and the Epigenetic Mechanisms That Break the Weismann Barrier.Journal of developmental biology · 2021Review
- Adaptation to simultaneous warming and acidification carries a thermal tolerance cost in a marine copepod.Biology letters · 2021Article
- Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity.Nature communications · 2021Article
- Complex pleiotropic genetic architecture of evolved heat stress and oxidative stress resistance in the nematode Caenorhabditis remanei.G3 (Bethesda, Md.) · 2021Article
- Nutrition-responsive gene expression and the developmental evolution of insect polyphenism.Nature ecology & evolution · 2020Article
- Chromosome-Level Assembly of theGenetics · 2020Article
- Ecological genomics of adaptation to unpredictability in experimental rotifer populations.Scientific reports · 2019Article
- Adaptation to climate change through genetic accommodation and assimilation of plastic phenotypes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Environmental and Evolutionary Drivers of the Modular Gene Regulatory Network Underlying Phenotypic Plasticity for Stress Resistance in the NematodeG3 (Bethesda, Md.) · 2019Article
- Plasticity-led evolution: evaluating the key prediction of frequency-dependent adaptation.Proceedings. Biological sciences · 2019Article
- Genomics of Developmental Plasticity in Animals.Frontiers in genetics · 2019Review
- Limited social plasticity in the socially polymorphic sweat beeBehavioral ecology and sociobiology · 2018Article
- Modularity Facilitates Flexible Tuning of Plastic and Evolutionary Gene Expression Responses during Early Divergence.Genome biology and evolution · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Many organisms can acclimate to new environments through phenotypic plasticity, a complex trait that can be heritable, subject to selection, and evolve. However, the rate and genetic basis of plasticity evolution remain largely unknown. We experimentally evolved outbred populations of the nematode Caenorhabditis remanei under an acute heat shock during early larval development. When raised in a nonstressful environment, ancestral populations were highly sensitive to a 36.8° heat shock and exhibited high mortality. However, initial exposure to a nonlethal high temperature environment resulted in significantly reduced mortality during heat shock (hormesis). Lines selected for heat shock resistance rapidly evolved the capacity to withstand heat shock in the native environment without any initial exposure to high temperatures, and early exposure to high temperatures did not lead to further increases in heat resistance. This loss of plasticity would appear to have resulted from the genetic assimilation of the heat induction response in the noninducing environment. However, analyses of transcriptional variation via RNA-sequencing from the selected populations revealed no global changes in gene regulation correlated with the observed changes in heat stress resistance. Instead, assays of the phenotypic response across a broader range of temperatures revealed that the induced plasticity was not fixed across environments, but rather the threshold for the response was shifted to higher temperatures over evolutionary time. These results demonstrate that apparent genetic assimilation can result from shifting thresholds of induction across environments and that analysis of the broader environmental context is critically important for understanding the evolution of phenotypic plasticity.
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Registered trials
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