ArticleApplied and environmental microbiology2014
High prevalence of Enterocytozoon bieneusi in asymptomatic pigs and assessment of zoonotic risk at the genotype level.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Global molecular epidemiology of microsporidia in pigs and wild boars with emphasis on Enterocytozoon bieneusi: A systematic review and meta-analysis.Veterinary medicine and science · 2022Pooled it
- Molecular detection and subtype characterization of Blastocystis in diarrheal outpatients in Shanghai, China: A case-control study.PLoS neglected tropical diseases · 2026Article
- Telomere-to-telomere genome assembly of Microsporidia sp. MB, a microsporidian symbiont of Anopheles coluzzii isolated from Burkina Faso.BMC genomics · 2026Article
- First molecular detection and genotyping of Enterocytozoon bieneusi (Microsporidia) in fattening pigs from Italy.BMC veterinary research · 2026Article
- Molecular characterization of Cryptosporidium spp. in goats (Capra hircus) from Zhejiang Province, China: evidence of zoonotic species and subtypes.BMC microbiology · 2026Article
- Molecular epidemiology ofFrontiers in cellular and infection microbiology · 2026Article
- Molecular identification and genotyping ofFood and waterborne parasitology · 2025Article
- PCR-based detection ofFrontiers in cellular and infection microbiology · 2025Article
- Dietary supplementation withMicrobiology spectrum · 2024Article
- Molecular prevalence and genotype identification ofFrontiers in veterinary science · 2024Article
- Brown rats (Frontiers in veterinary science · 2024Article
- A baseline epidemiological study of the co-infection of enteric protozoans with human immunodeficiency virus among men who have sex with men from Northeast China.PLoS neglected tropical diseases · 2022Article
- Prevalence and genotyping distribution ofFrontiers in microbiology · 2022Article
- Ecological and public health significance ofOne health (Amsterdam, Netherlands) · 2021Review
- Molecular detection of porcine Enterocytozoon bieneusi infection in Peninsular Malaysia and epidemiological risk factors associated with potentially zoonotic genotypes.Parasitology research · 2020Article
- Novel genotypes and multilocus genotypes of Enterocytozoon bieneusi in two wild rat species in China: potential for zoonotic transmission.Parasitology research · 2020Article
- Multilocus Sequence Typing ofFrontiers in microbiology · 2020Article
- Molecular detection of Enterocytozoon bieneusi in farm-raised pigs in Hainan Province, China: infection rates, genotype distributions, and zoonotic potential.Parasite (Paris, France) · 2020Article
- Molecular characterization and distribution of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi from yaks in Tibet, China.BMC veterinary research · 2019Article
- "Enterocytozoon bieneusi and Cryptosporidium: a cross-sectional study conducted throughout Thailand".BMC infectious diseases · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enterocytozoon bieneusi is an emerging and clinically significant enteric parasite infecting humans and animals and can cause life-threatening diarrhea in immunocompromised people. Pigs are considered to be one of the main reservoir hosts of E. bieneusi based on their high prevalence rates and zoonotic genotypes in pigs. As an opportunistic pathogen, E. bieneusi infection of pigs can be inapparent, which leads to neglect in detecting this parasite in pigs and assessing the epidemiological role of pigs in the transmission of human microsporidiosis. In the present study, 95 healthy pigs aged 2 or 3 months were randomly selected from three areas in Heilongjiang Province, China. E. bieneusi isolates were identified and genotyped based on the small-subunit (SSU) rRNA and internal transcribed spacer (ITS) regions of the rRNA gene by PCR and sequencing. A high prevalence of E. bieneusi was observed, 83.2% (79/95) at the SSU rRNA locus versus 89.5% (85/95) at the ITS locus. Ten ITS genotypes were obtained, comprising six known genotypes—EbpA (n = 30), D (n = 19), H (n = 18), O (n = 11), CS-1 (n = 1), and LW1 (n = 1)—and four novel genotypes named HLJ-I to HLJ-IV; 70.6% (60/85) of E. bieneusi genotypes were zoonotic (genotypes EbpA, D, and O). The findings of a high prevalence of E. bieneusi in pigs and a large percentage of zoonotic genotypes indicate that pigs may play a role in the transmission of E. bieneusi to humans and may become an important source of water contamination in our investigated areas.
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