Evidence map›Paper›PMID 24727147›Full record

ReviewMethods (San Diego, Calif.)2014

Methods to assess Drosophila heart development, function and aging.

Karen Ocorr, Georg Vogler, Rolf Bodmer

Abstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Article
  3. Exercise ModulatesInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Analysis ofAmerican journal of physiology. Heart and circulatory physiology · 2022
    Article
  17. Article
  18. Identification of Bipotential Blood Cell/Nephrocyte Progenitors inFrontiers in cell and developmental biology · 2022
    Article
  19. Reduction ofFrontiers in cell and developmental biology · 2022
    Article
  20. Experimental models of Barth syndrome.Journal of inherited metabolic disease · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karen OcorrDevelopment, Aging and Regeneration Program, Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Rd., La Jolla, CA 92037, United States. Electronic address: kocorr@sbmri.org.
Georg VoglerDevelopment, Aging and Regeneration Program, Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Rd., La Jolla, CA 92037, United States.
Rolf BodmerDevelopment, Aging and Regeneration Program, Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Rd., La Jolla, CA 92037, United States. Electronic address: rolf@sbmri.org.
Sanford Burnham Prebys Medical Discovery Institute · US

Funding

HEART DEVELOPMENT IN DROSOPHILAR01HL054732 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BODMER, ROLF · 1995 to 2024
$11.3M
Systems Biology CoreP01HL098053 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HADDAD, GABRIEL G · 2010 to 2014
$10.2M
GENETIC ANALYSIS OF SLEEP SENECENCEP01AG033561 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BODMER, ROLF · 2011 to 2015
$6.3M
NHLBI NIH HHS P01 HL098053NHLBI NIH HHS R01 HL054732NIA NIH HHS P01 AG033561
6 · The paper itself

Abstract

In recent years the Drosophila heart has become an established model for many different aspects of human cardiac disease. This model has allowed identification of disease-causing mechanisms underlying congenital heart disease and cardiomyopathies and has permitted the study of underlying genetic, metabolic and age-related contributions to heart function. In this review we discuss methods currently employed in the analysis of the Drosophila heart structure and function, such as optical methods to infer heart function and performance, electrophysiological and mechanical approaches to characterize cardiac tissue properties, and conclude with histological techniques used in the study of heart development and adult structure.

Indexed as

AgingAnimalsDevelopmental BiologyDrosophilaDrosophila ProteinsHeartHumansDrosophila ProteinsAtomic force microscopyCardiomyopathyDevelopmentDrosophilaElectrophysiologyHeartImmunohistochemistryKCNQOptical heartbeat analysisTinman

Identifiers

PMID24727147
PMCPMC4058868
OpenAlexW2028030689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.