Evidence map›Paper›PMID 24726345›Full record

ArticleTrends in ecology & evolution2014

Assembling evidence for identifying reservoirs of infection.

Mafalda Viana, Rebecca Mancy, Roman Biek, Sarah Cleaveland, Paul C Cross, James O Lloyd-Smith, Daniel T Haydon

Abstract read
In one paragraph

Article in Trends in ecology & evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  6. Prioritizing surveillance of Nipah virus in India.PLoS neglected tropical diseases · 2019
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  13. Isolation ofOne health (Amsterdam, Netherlands) · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mafalda VianaBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address: mafalda.viana@glasgow.ac.uk.
Rebecca MancyBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK; School of Computing Science, University of Glasgow, Glasgow G12 8QQ, UK.
Roman BiekBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK; Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA.
Sarah CleavelandBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
Paul C CrossUS Geological Survey, Northern Rocky Mountain Science Center 2327, University Way, Suite 2, Bozeman, MT 59715, USA.
James O Lloyd-SmithFogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA; Department of Ecology and Evolutionary Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
Daniel T HaydonBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.

Funding

SPATIAL POPULATION DYNAMICS OF RABIESR01AI047498 · NIAID · EMORY UNIVERSITY · PI REAL, LESLIE A. · 1999 to 2014
$3.6M
Biotechnology and Biological Sciences Research Council BB/H009035/1Biotechnology and Biological Sciences Research Council BB/H009302/1Biotechnology and Biological Sciences Research Council BB/J010367/1Medical Research Council G0901135NIAID NIH HHS R01 AI047498
6 · The paper itself

Abstract

Many pathogens persist in multihost systems, making the identification of infection reservoirs crucial for devising effective interventions. Here, we present a conceptual framework for classifying patterns of incidence and prevalence, and review recent scientific advances that allow us to study and manage reservoirs simultaneously. We argue that interventions can have a crucial role in enriching our mechanistic understanding of how reservoirs function and should be embedded as quasi-experimental studies in adaptive management frameworks. Single approaches to the study of reservoirs are unlikely to generate conclusive insights whereas the formal integration of data and methodologies, involving interventions, pathogen genetics, and contemporary surveillance techniques, promises to open up new opportunities to advance understanding of complex multihost systems.

Indexed as

AnimalsCommunicable DiseasesDisease ReservoirsEpidemiologic FactorsHumansZoonoses

Identifiers

PMID24726345
PMCPMC4007595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.