Evidence map›Paper›PMID 24726318›Full record

ArticleDrug and alcohol dependence2014

Stimulant use and HIV disease management among men in same-sex relationships.

Adam W Carrico, Sarah E Woolf-King, Torsten B Neilands, Samantha E Dilworth, Mallory O Johnson

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Article
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  7. Article
  8. HIV and Substance Use Disorders.Infectious disease clinics of North America · 2024
    Review
  9. Article
  10. Overamped: Stimulant Use and HIV Pathogenesis.Current HIV/AIDS reports · 2023
    Review
  11. Article
  12. Article
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  20. Stimulant use patterns and HIV transmission risk among HIV-serodiscordant male couples.Journal of acquired immune deficiency syndromes (1999) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adam W CarricoUniversity of California, San Francisco, School of Nursing, United States; University of California, San Francisco, Center for AIDS Prevention Studies (CAPS), United States. Electronic address: adam.carrico@ucsf.edu.
Sarah E Woolf-KingUniversity of California, San Francisco, Center for AIDS Prevention Studies (CAPS), United States.
Torsten B NeilandsUniversity of California, San Francisco, Center for AIDS Prevention Studies (CAPS), United States.
Samantha E DilworthUniversity of California, San Francisco, Center for AIDS Prevention Studies (CAPS), United States.
Mallory O JohnsonUniversity of California, San Francisco, School of Nursing, United States; University of California, San Francisco, Center for AIDS Prevention Studies (CAPS), United States; University of California, San Francisco, School of Pharmacy, United States.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
The role of relationship stigma on HIV outcomes among sexual and gender minority couplesR01NR010187 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2006 to 2020
$7.5M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Alcohol Use and High Risk Behavior Among HIV-Positive MenK01AA021671 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOOLF-KING, SARAH E · 2013 to 2017
$865k
Dyadic Processes in the Patient-Provider RelationshipK24MH087220 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2009 to 2013
$771k
NIAAA NIH HHS K01 AA021671NIAID NIH HHS P30 AI027763NIDA NIH HHS K24 DA037034NIMH NIH HHS K24 MH087220NIMH NIH HHS K24-MH087220NIMH NIH HHS P30 MH062246NIMH NIH HHS T32 MH019105NINR NIH HHS R01 NR010187NINR NIH HHS R01-NR010187
6 · The paper itself

Abstract

backgroundResearch conducted to date has focused primarily on identifying individual-level, psychological determinants of stimulant use and HIV disease management. The present cross-sectional study examined relationship factors as correlates of stimulant use and HIV disease management among men who have sex with men (MSM).

methodsIn total, 266 male couples completed a baseline assessment for a cohort study examining the role of relationship factors in HIV treatment. A computer-based assessment of relationship factors, self-reported alcohol and substance use, and self-reported anti-retroviral therapy (ART) adherence was administered. All HIV-positive participants also provided a blood sample to measure viral load.

resultsAfter controlling for demographic characteristics and relationship factors, men in a primary relationship with a stimulant-using partner had more than six-fold greater odds of reporting any stimulant use in the past three months. Among HIV-positive participants on ART (n=371), having a stimulant-using partner was independently associated with 67% lower odds of reporting perfect 30-day ART adherence and more than two-fold greater odds of displaying a detectable HIV viral load. In contrast, more partner-level alcohol use was independently associated with greater odds of reporting perfect 3-day ART adherence and lower odds of displaying a detectable HIV viral load.

conclusionsPartner-level stimulant use is an important risk factor for individual-level stimulant use and difficulties with HIV disease management among MSM. To optimize the effectiveness of HIV treatment as prevention, clinical research is needed to develop couples-based interventions targeting stimulant use as a potential driver of detectable HIV viral load.

Indexed as

Central Nervous System StimulantsAnti-HIV AgentsCross-Sectional StudiesDrug MonitoringHIV InfectionsHomosexuality, MaleHumansInterpersonal RelationsMaleMedication AdherenceMiddle AgedPsychological TestsSubstance-Related DisordersSurveys and QuestionnairesViral LoadAnti-HIV AgentsCentral Nervous System StimulantsAdherenceCocaineHIVMethamphetamineTreatment as preventionViral load

Identifiers

PMID24726318
PMCPMC4048569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.