Evidence map›Paper›PMID 24725981›Full record

ReviewAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2014

Loin pain hematuria syndrome.

Sahar Taba Taba Vakili, Tausif Alam, Hans Sollinger

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Loin Pain Hematuria Syndrome-a case report.Journal of surgical case reports · 2021
    Article
  6. Nutcracker syndrome: diagnosis and therapy.Cardiovascular diagnosis and therapy · 2021
    Review
  7. Treatment and Management of Loin Pain Hematuria Syndrome.Current pain and headache reports · 2021
    Review
  8. Review
  9. Renal autotransplantation results in pain resolution after left renal vein transposition.Journal of vascular surgery. Venous and lymphatic disorders · 2019
    Article
  10. The "UW-LPHS Test": A New Test to Predict the Outcome of Renal Autotransplant for Loin Pain Hematuria Syndrome.Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation · 2018
    Article
  11. Chronic renal pain: An approach to investigation and management.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Review
  12. Article
  13. Commentary: Loin Pain Hematuria Syndrome.Journal of rare diseases research & treatment · 2018
    Article
  14. Review
  15. Loin pain hematuria syndrome.Clinical kidney journal · 2016
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sahar Taba Taba VakiliDivision of Transplantation, Department of Surgery, University of Wisconsin, Madison, WI.
Tausif AlamDivision of Transplantation, Department of Surgery, University of Wisconsin, Madison, WI.
Hans SollingerDivision of Transplantation, Department of Surgery, University of Wisconsin, Madison, WI. Electronic address: hans@surgery.wisc.edu.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loin pain hematuria syndrome is a rare disease with a prevalence of ∼0.012%. The most prominent clinical features include periods of severe intermittent or persistent unilateral or bilateral loin pain accompanied by either microscopic or gross hematuria. Patients with loin pain hematuria syndrome initially present with hematuria, flank pain, or most often both hematuria and flank pain. Kidney biopsies from patients with loin pain hematuria typically reveal only minor pathologic abnormalities. Further, loin pain hematuria syndrome is not associated with loss of kidney function or urinary tract infections. Loin pain hematuria syndrome-associated hematuria and pain are postulated to be linked to vascular disease of the kidney, coagulopathy, renal vasospasm with microinfarction, hypersensitivity, complement activation on arterioles, venocalyceal fistula, abnormal ureteral peristalsis, and intratubular deposition of calcium or uric acid microcrystals. Many patients with loin pain hematuria syndrome also meet criteria for a somatoform disorder, and analgesic medications, including narcotics, commonly are used to treat loin pain hematuria syndrome-associated pain. Interventional treatments include renal denervation, kidney autotransplantation, and nephrectomy; however, these methods should be used only as a last resort when less invasive measures have been tried unsuccessfully. In this review article, we discuss and critique current clinical practices related to loin pain hematuria syndrome pathophysiology, diagnosis, treatment, and prognosis.

Indexed as

Flank PainHematuriaAdultFemaleHumansSyndromehematurialoin painLoin pain hematuria syndrome (LPHS)renal autotransplantationrenal denervation

Identifiers

PMID24725981
OpenAlexW2079649329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.