Trial reportEarly intervention in psychiatry2016
Family-focused therapy for individuals at clinical high risk for psychosis: treatment fidelity within a multisite randomized trial.
Trial report in Early intervention in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04338152 (Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Psychological interventions for psychosis in adolescents.The Cochrane database of systematic reviews · 2020Pooled it
- Assessing Implementation Strategy Reporting in the Mental Health Literature: A Narrative Review.Administration and policy in mental health · 2020Pooled it
- Interventions for prodromal stage of psychosis.The Cochrane database of systematic reviews · 2019Pooled it
- Early Family Intervention for Youth at Risk for Bipolar Disorder: Psychosocial and Neural Mediators of Outcome.Current neuropharmacology · 2023Trial
- Family-focused therapy for individuals at high clinical risk for psychosis: A confirmatory efficacy trial.Early intervention in psychiatry · 2022Trial
- Effects of High- versus Low-Intensity Clinician Training on Implementation of Family-Focused Therapy for Youth with Mood and Psychotic Disorders.Family process · 2021Trial
- A Randomized Comparison of Two Psychosocial Interventions on Family Functioning in Adolescents with Bipolar Disorder.Family process · 2020Trial
- Effects of Family-Focused Therapy vs Enhanced Usual Care for Symptomatic Youths at High Risk for Bipolar Disorder: A Randomized Clinical Trial.JAMA psychiatry · 2020Trial
- Therapist adherence to family-based treatment for adolescents with anorexia nervosa: A multi-site exploratory study.European eating disorders review : the journal of the Eating Disorders Association · 2020Trial
- Decreases in perceived maternal criticism predict improvement in subthreshold psychotic symptoms in a randomized trial of family-focused therapy for individuals at clinical high risk for psychosis.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2015Trial
- Family-focused treatment for adolescents and young adults at high risk for psychosis: results of a randomized trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2014Trial
- A randomized trial of family focused therapy with populations at clinical high risk for psychosis: effects on interactional behavior.Journal of consulting and clinical psychology · 2014Trial
- Feasibility and acceptability of a contextualized brief psychological intervention for people with bipolar disorder in rural Ethiopia.Pilot and feasibility studies · 2025Article
- A Randomized Clinical Trial of Technology-Enhanced Family-Focused Therapy for Youth in the Early Stages of Mood Disorders.JAACAP open · 2023Article
- Clues from caregiver emotional language usage highlight the link between putative social environment and the psychosis-risk syndrome.Schizophrenia research · 2023Article
- Family-based treatment for children and adolescents with eating disorders: a mixed-methods evaluation of a blended evidence-based implementation approach.Translational behavioral medicine · 2021Article
- Early Interventions for Clinical High-Risk State for Psychosis.Noro psikiyatri arsivi · 2021Review
- Advances in clinical staging, early intervention, and the prevention of psychosis.F1000Research · 2019Review
- Family-Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research.Family process · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimFamily psychoeducation is an effective adjunct to pharmacotherapy in delaying relapse among patients with schizophrenia and bipolar disorder. This study tested the treatment adherence and competence of newly trained clinicians to an adaptation of family-focused therapy for individuals at clinical high risk for psychosis (FFT-CHR).
methodsThe sample included 103 youth or young adults (ages 12-30 years) who had attenuated positive symptoms of psychosis. Families participated in a randomized trial comparing two psychosocial interventions: FFT-CHR (18 sessions over 6 months) and enhanced care (EC; 3 sessions over 1 month). Following a 1.5-day training seminar, 24 clinicians from eight study sites received teleconference supervision in both treatment protocols for the 2-year study period. Treatment fidelity was rated with the 13-item Therapy Competence and Adherence Scales, Revised.
resultsSupervisors classified 90% of treatment sessions as above acceptable fidelity thresholds (ratings of 5 or better on a 1-7 scale of overall fidelity). As expected, fidelity ratings indicated that FFT-CHR included a greater emphasis on communication and problem-solving skills training than EC, but ratings of non-specific clinician skills, such as maintaining rapport and appropriately pacing sessions, did not differ between conditions. Treatment fidelity was not related to the severity of symptoms or family conflict at study entry.
conclusionsFFT-CHR can be administered with high levels of fidelity by clinicians who receive training and supervision. Future studies should examine whether there are more cost-effective methods for training, supervising and monitoring the fidelity of FFT-CHR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.